UniProt P0ADY7
50S ribosomal protein L16 (P0ADY7)
50S ribosomal protein L16 (UniProt P0ADY7): 192 experimental structures and 1 predicted model on GenesisL1, 7 ligands bound, 56 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P0ADY7
- Protein
- 50S ribosomal protein L16
- Experimental structures
- 192
- Predicted models
- 1
- Ligands
- 7
- Pockets
- 56 · 47 records with a druggable one
Structures
193 records of P0ADY7 in the MolNFT archive: 192 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2J28 | Model of E. COLI srp bound to 70S rncs | electron microscopy | M | — | — |
| 2J28 | Model of E. COLI srp bound to 70S rncs | electron microscopy | M | — | — |
| 2RDO | 50S subunit with EF-G(GDPNP) and RRF bound | electron microscopy | M | — | — |
| 2RDO | 50S subunit with ef-G(GDPNP) and rrf bound | electron microscopy | M | — | — |
| 3J5L | Structure of the E. coli 50S subunit with ErmBL nascent chain | electron microscopy | M | — | — |
| 3J5L | Structure of the E. COLI 50S subunit with ermbl nascent chain | electron microscopy | M | — | — |
| 3J7Z | Structure of the E. coli 50S subunit with ErmCL nascent chain | electron microscopy | M | — | — |
| 3J7Z | Structure of the E. COLI 50S subunit with ermcl nascent chain | electron microscopy | M | — | — |
| 3J9Y | Cryo-EM structure of tetracycline resistance protein TetM bound to a translating E.coli ribosome | electron microscopy | M | — | — |
| 3J9Z | Activation of GTP Hydrolysis in mRNA-tRNA Translocation by Elongation Factor G | electron microscopy | LI | — | — |
| 3JA1 | Activation of GTP Hydrolysis in mRNA-tRNA Translocation by Elongation Factor G | electron microscopy | LO | — | — |
| 3JBU | Mechanisms of Ribosome Stalling by SecM at Multiple Elongation Steps | electron microscopy | m | — | — |
| 3JBV | Mechanisms of Ribosome Stalling by SecM at Multiple Elongation Steps | electron microscopy | m | — | — |
| 3JCD | Structure of Escherichia coli EF4 in posttranslocational ribosomes (Post EF4) | electron microscopy | M | — | — |
| 3JCE | Structure of Escherichia coli EF4 in pretranslocational ribosomes (Pre EF4) | electron microscopy | M | — | — |
| 3JCJ | Structures of ribosome-bound initiation factor 2 reveal the mechanism of subunit association | electron microscopy | L | — | — |
| 3JCN | Structures of ribosome-bound initiation factor 2 reveal the mechanism of subunit association… | electron microscopy | M | — | — |
| 4CSU | Cryo-EM structures of the 50S ribosome subunit bound with ObgE | electron microscopy | M | — | — |
| 4CSU | Cryo-EM structures of the 50S ribosome subunit bound with obge | electron microscopy | M | — | — |
| 4U1U | Crystal structure of the E. coli ribosome bound to quinupristin. | x-ray diffraction | BM, DM | — | — |
| 4U1V | Crystal structure of the E. coli ribosome bound to linopristin. | x-ray diffraction | BM, DM | — | — |
| 4U20 | Crystal structure of the E. coli ribosome bound to flopristin. | x-ray diffraction | BM, DM | — | — |
| 4U24 | Crystal structure of the E. coli ribosome bound to dalfopristin. | x-ray diffraction | BM, DM | — | — |
| 4U25 | Crystal structure of the E. coli ribosome bound to virginiamycin M1. | x-ray diffraction | BM, DM | — | — |
| 4U26 | Crystal structure of the E. coli ribosome bound to dalfopristin and quinupristin. | x-ray diffraction | BM, DM | — | — |
| 4U27 | Crystal structure of the E. coli ribosome bound to flopristin and linopristin. | x-ray diffraction | BM, DM | — | — |
| 4V4V | Structure of a pre-translocational E. coli ribosome obtained by fitting atomic models for RNA and… | electron microscopy | BK | — | — |
| 4V4W | Structure of a SecM-stalled E. coli ribosome complex obtained by fitting atomic models for RNA and… | electron microscopy | BK | — | — |
| 4V50 | Crystal Structure of Ribosome with messenger RNA and the Anticodon stem-loop of P-site tRNA. | x-ray diffraction | BM, DM | — | — |
| 4V52 | Crystal structure of the bacterial ribosome from Escherichia coli in complex with neomycin. | x-ray diffraction | BM, DM | — | — |
| 4V53 | Crystal structure of the bacterial ribosome from Escherichia coli in complex with gentamicin. | x-ray diffraction | BM, DM | — | — |
| 4V54 | Crystal structure of the bacterial ribosome from Escherichia coli in complex with ribosome… | x-ray diffraction | BM, DM | — | — |
| 4V55 | Crystal structure of the bacterial ribosome from Escherichia coli in complex with gentamicin and… | x-ray diffraction | BM, DM | — | — |
| 4V56 | Crystal structure of the bacterial ribosome from Escherichia coli in complex with spectinomycin. | x-ray diffraction | BM, DM | — | — |
| 4V57 | Crystal structure of the bacterial ribosome from Escherichia coli in complex with spectinomycin and… | x-ray diffraction | BM, DM | — | — |
| 4V5B | Structure of PDF binding helix in complex with the ribosome. | x-ray diffraction | AM, CM | — | — |
| 4V5H | E.Coli 70s Ribosome Stalled During Translation Of Tnac Leader Peptide. | electron microscopy | BM | — | — |
| 4V5Y | Crystal structure of the bacterial ribosome from Escherichia coli in complex with paromomycin and… | x-ray diffraction | BM, DM | — | — |
| 4V65 | Structure of the E. coli ribosome in the Pre-accommodation state | electron microscopy | BF | — | — |
| 4V66 | Structure of the E. coli ribosome and the tRNAs in Post-accommodation state | electron microscopy | BF | — | — |
| 4V69 | Ternary complex-bound E.coli 70S ribosome. | electron microscopy | BM | — | — |
| 4V6C | Crystal structure of the E. coli 70S ribosome in an intermediate state of ratcheting | x-ray diffraction | BM, DM | — | — |
| 4V6D | Crystal structure of the E. coli 70S ribosome in an intermediate state of ratcheting | x-ray diffraction | BM, DM | — | — |
| 4V6E | Crystal structure of the E. coli 70S ribosome in an intermediate state of ratcheting | x-ray diffraction | BM, DM | — | — |
| 4V6K | Structural insights into cognate vs. near-cognate discrimination during decoding. | electron microscopy | AN | — | — |
| 4V6L | Structural insights into cognate vs. near-cognate discrimination during decoding. | electron microscopy | BN | — | — |
| 4V6M | Structure of the ribosome-SecYE complex in the membrane environment | electron microscopy | BM | — | — |
| 4V6N | Structural characterization of mRNA-tRNA translocation intermediates (50S ribosome of class2 of the… | electron microscopy | AO | — | — |
| 4V6O | Structural characterization of mRNA-tRNA translocation intermediates (class 4a of the six classes) | electron microscopy | BO | — | — |
| 4V6P | Structural characterization of mRNA-tRNA translocation intermediates (class 4b of the six classes) | electron microscopy | BO | — | — |
| 4V6Q | Structural characterization of mRNA-tRNA translocation intermediates (class 5 of the six classes) | electron microscopy | BO | — | — |
| 4V6R | Structural characterization of mRNA-tRNA translocation intermediates (class 6 of the six classes) | electron microscopy | BO | — | — |
| 4V6S | Structural characterization of mRNA-tRNA translocation intermediates (class 3 of the six classes) | electron microscopy | AO | — | — |
| 4V6T | Structure of the bacterial ribosome complexed by tmRNA-SmpB and EF-G during translocation and… | electron microscopy | BM | — | — |
| 4V6V | Tetracycline resistance protein Tet(O) bound to the ribosome | electron microscopy | BQ | — | — |
| 4V6Y | E. coli 70S-fMetVal-tRNAVal-tRNAfMet complex in classic pre-translocation state (pre1a) | electron microscopy | BM | — | — |
| 4V6Z | E. coli 70S-fMetVal-tRNAVal-tRNAfMet complex in classic pre-translocation state (pre1b) | electron microscopy | BM | — | — |
| 4V70 | E. coli 70S-fMetVal-tRNAVal-tRNAfMet complex in intermediate pre-translocation state (pre3) | electron microscopy | BM | — | — |
| 4V71 | E. coli 70S-fMetVal-tRNAVal-tRNAfMet complex in intermediate pre-translocation state (pre2) | electron microscopy | BM | — | — |
| 4V72 | E. coli 70S-fMetVal-tRNAVal-tRNAfMet complex in hybrid pre-translocation state (pre4) | electron microscopy | BM | — | — |
133 records more on the page itself.
Ligands
- MG · Magnesium ion · in 15 records
- PUT · 1,4-diaminobutane · in 3 records
- K · Potassium ion · in 2 records
- 6UQ · (2R,3S,4R,6S)-4-hydroxy-6-{[(2R,3aR,4R,4'R,5'S,6S,6'R,7aR)-4'-hydroxy-6-{[(2S,3R,4R,5S,6R)-3-hydroxy-2-{[(2R,3S,4S,5S,6S)-4-hydroxy-6-({(2R,3aS,3a'R,6S,6'R,7R,7'R,7aR,7a'R)-7'-hydroxy-7'-[(1S)-1-hydroxyethyl]-6'-methyl-7-[(2-methylpropanoyl)oxy]octahydro-4H-2,4'-spirobi[[1,3]dioxolo[4,5-c]pyran]-6-yl}oxy)-5-methoxy-2-(methoxymethyl)tetrahydro-2H-pyran-3-yl]oxy}-5-methoxy-6-methyltetrahydro-2H-pyran-4-yl]oxy}-4,6',7a-trimethyloctahydro-4H-spiro[1,3-dioxolo[4,5-c]pyran-2,2'-pyran]-5'-yl]oxy}-2-met · in 1 record
- EVN · (2R,3R,4R,6S)-6-{[(2R,3aR,4R,4'R,5'S,6S,6'R,7S,7aR)-6-{[(2S,3R,4R,5S,6R)-2-{[(2R,3S,4S,5S,6S)-6-({(2R,3aS,3a'R,6S,7R,7' R,7aS,7a'S)-7'-[(2,4-dihydroxy-6-methylbenzoyl)oxy]-7-hydroxyoctahydro-4H-2,4'-spirobi[[1,3]dioxolo[4,5-c]pyran]-6-yl}ox y)-4-hydroxy-5-methoxy-2-(methoxymethyl)tetrahydro-2H-pyran-3-yl]oxy}-3-hydroxy-5-methoxy-6-methyltetrahydro-2H-pyran-4- yl]oxy}-4',7-dihydroxy-4,6',7a-trimethyloctahydro-4H-spiro[1,3-dioxolo[4,5-c]pyran-2,2'-pyran]-5'-yl]oxy}-4-{[(2R,4S,5R, 6S)-5-methoxy-4,6 · in 1 record
- NA · Sodium ion · in 1 record
- UNX · Unknown atom or ion · in 1 record
Experiment against prediction
- 7N30 chain LP against the predicted model P0ADY7: TM-score 1.00, RMSD 0.29 Å
- 7Y7C chain l against the predicted model P0ADY7: TM-score 1.00, RMSD 0.30 Å
- 6ZTP chain BN against the predicted model P0ADY7: TM-score 1.00, RMSD 0.30 Å
- 7O1A chain BM against the predicted model P0ADY7: TM-score 1.00, RMSD 0.30 Å
- 7Y7E chain l against the predicted model P0ADY7: TM-score 0.99, RMSD 0.32 Å
- 7Y7F chain l against the predicted model P0ADY7: TM-score 0.99, RMSD 0.32 Å
- 8CEU chain l against the predicted model P0ADY7: TM-score 0.99, RMSD 0.32 Å
- 8YUQ chain l against the predicted model P0ADY7: TM-score 0.99, RMSD 0.33 Å
- 6ORE chain M against the predicted model P0ADY7: TM-score 0.99, RMSD 0.33 Å
- 7NWT chain M against the predicted model P0ADY7: TM-score 0.99, RMSD 0.33 Å
Elsewhere
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