UniProt P60422
50S ribosomal protein L2 (P60422)
50S ribosomal protein L2 (UniProt P60422): 275 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 340 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P60422
- Protein
- 50S ribosomal protein L2
- Experimental structures
- 275
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 340 · 110 records with a druggable one
Structures
276 records of P60422 in the MolNFT archive: 275 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2J28 | Model of E. COLI srp bound to 70S rncs | electron microscopy | C | — | — |
| 2RDO | 50S subunit with EF-G(GDPNP) and RRF bound | electron microscopy | C | — | — |
| 2RDO | 50S subunit with ef-G(GDPNP) and rrf bound | electron microscopy | C | — | — |
| 3BBX | The Hsp15 protein fitted into the low resolution Cryo-EM map of the 50S.nc-tRNA.Hsp15 complex | electron microscopy | C | — | — |
| 3BBX | The HSP15 protein fitted into the low resolution cryo-EM MAP of the 50S.NC-TRNA.HSP15 complex | electron microscopy | C | — | — |
| 3J5L | Structure of the E. coli 50S subunit with ErmBL nascent chain | electron microscopy | C | — | — |
| 3J5L | Structure of the E. COLI 50S subunit with ermbl nascent chain | electron microscopy | C | — | — |
| 3J7Z | Structure of the E. coli 50S subunit with ErmCL nascent chain | electron microscopy | C | — | — |
| 3J7Z | Structure of the E. COLI 50S subunit with ermcl nascent chain | electron microscopy | C | — | — |
| 3J9Y | Cryo-EM structure of tetracycline resistance protein TetM bound to a translating E.coli ribosome | electron microscopy | C | — | — |
| 3J9Z | Activation of GTP Hydrolysis in mRNA-tRNA Translocation by Elongation Factor G | electron microscopy | LN | — | — |
| 3JA1 | Activation of GTP Hydrolysis in mRNA-tRNA Translocation by Elongation Factor G | electron microscopy | LD | — | — |
| 3JBU | Mechanisms of Ribosome Stalling by SecM at Multiple Elongation Steps | electron microscopy | c | — | — |
| 3JBV | Mechanisms of Ribosome Stalling by SecM at Multiple Elongation Steps | electron microscopy | c | — | — |
| 3JCD | Structure of Escherichia coli EF4 in posttranslocational ribosomes (Post EF4) | electron microscopy | C | — | — |
| 3JCE | Structure of Escherichia coli EF4 in pretranslocational ribosomes (Pre EF4) | electron microscopy | C | — | — |
| 3JCJ | Structures of ribosome-bound initiation factor 2 reveal the mechanism of subunit association | electron microscopy | B | — | — |
| 3JCN | Structures of ribosome-bound initiation factor 2 reveal the mechanism of subunit association… | electron microscopy | C | — | — |
| 4CSU | Cryo-EM structures of the 50S ribosome subunit bound with ObgE | electron microscopy | C | — | — |
| 4CSU | Cryo-EM structures of the 50S ribosome subunit bound with obge | electron microscopy | C | — | — |
| 4U1U | Crystal structure of the E. coli ribosome bound to quinupristin. | x-ray diffraction | BC, DC | — | — |
| 4U1V | Crystal structure of the E. coli ribosome bound to linopristin. | x-ray diffraction | BC, DC | — | — |
| 4U20 | Crystal structure of the E. coli ribosome bound to flopristin. | x-ray diffraction | BC, DC | — | — |
| 4U24 | Crystal structure of the E. coli ribosome bound to dalfopristin. | x-ray diffraction | BC, DC | — | — |
| 4U25 | Crystal structure of the E. coli ribosome bound to virginiamycin M1. | x-ray diffraction | BC, DC | — | — |
| 4U26 | Crystal structure of the E. coli ribosome bound to dalfopristin and quinupristin. | x-ray diffraction | BC, DC | — | — |
| 4U27 | Crystal structure of the E. coli ribosome bound to flopristin and linopristin. | x-ray diffraction | BC, DC | — | — |
| 4V47 | Real space refined coordinates of the 30S and 50S subunits fitted into the low resolution cryo-EM… | electron microscopy | AA | — | — |
| 4V48 | Real space refined coordinates of the 30S and 50S subunits fitted into the low resolution cryo-EM… | electron microscopy | AA | — | — |
| 4V4H | Crystal structure of the bacterial ribosome from Escherichia coli in complex with the antibiotic… | x-ray diffraction | BC, DC | — | — |
| 4V4Q | Crystal structure of the bacterial ribosome from Escherichia coli at 3.5 A resolution. | x-ray diffraction | BC, DC | — | — |
| 4V4V | Structure of a pre-translocational E. coli ribosome obtained by fitting atomic models for RNA and… | electron microscopy | BA | — | — |
| 4V4W | Structure of a SecM-stalled E. coli ribosome complex obtained by fitting atomic models for RNA and… | electron microscopy | BA | — | — |
| 4V50 | Crystal Structure of Ribosome with messenger RNA and the Anticodon stem-loop of P-site tRNA. | x-ray diffraction | BC, DC | — | — |
| 4V52 | Crystal structure of the bacterial ribosome from Escherichia coli in complex with neomycin. | x-ray diffraction | BC, DC | — | — |
| 4V53 | Crystal structure of the bacterial ribosome from Escherichia coli in complex with gentamicin. | x-ray diffraction | BC, DC | — | — |
| 4V54 | Crystal structure of the bacterial ribosome from Escherichia coli in complex with ribosome… | x-ray diffraction | BC, DC | — | — |
| 4V55 | Crystal structure of the bacterial ribosome from Escherichia coli in complex with gentamicin and… | x-ray diffraction | BC, DC | — | — |
| 4V56 | Crystal structure of the bacterial ribosome from Escherichia coli in complex with spectinomycin. | x-ray diffraction | BC, DC | — | — |
| 4V57 | Crystal structure of the bacterial ribosome from Escherichia coli in complex with spectinomycin and… | x-ray diffraction | BC, DC | — | — |
| 4V5H | E.Coli 70s Ribosome Stalled During Translation Of Tnac Leader Peptide. | electron microscopy | BC | — | — |
| 4V5Y | Crystal structure of the bacterial ribosome from Escherichia coli in complex with paromomycin and… | x-ray diffraction | BC, DC | — | — |
| 4V64 | Crystal structure of the bacterial ribosome from Escherichia coli in complex with hygromycin B. | x-ray diffraction | BC, DC | — | — |
| 4V65 | Structure of the E. coli ribosome in the Pre-accommodation state | electron microscopy | BN | — | — |
| 4V66 | Structure of the E. coli ribosome and the tRNAs in Post-accommodation state | electron microscopy | BN | — | — |
| 4V69 | Ternary complex-bound E.coli 70S ribosome. | electron microscopy | BC | — | — |
| 4V6C | Crystal structure of the E. coli 70S ribosome in an intermediate state of ratcheting | x-ray diffraction | BC, DC | — | — |
| 4V6D | Crystal structure of the E. coli 70S ribosome in an intermediate state of ratcheting | x-ray diffraction | BC, DC | — | — |
| 4V6E | Crystal structure of the E. coli 70S ribosome in an intermediate state of ratcheting | x-ray diffraction | BC, DC | — | — |
| 4V6K | Structural insights into cognate vs. near-cognate discrimination during decoding. | electron microscopy | AD | — | — |
| 4V6L | Structural insights into cognate vs. near-cognate discrimination during decoding. | electron microscopy | BD | — | — |
| 4V6M | Structure of the ribosome-SecYE complex in the membrane environment | electron microscopy | B6 | — | — |
| 4V6N | Structural characterization of mRNA-tRNA translocation intermediates (50S ribosome of class2 of the… | electron microscopy | AD | — | — |
| 4V6O | Structural characterization of mRNA-tRNA translocation intermediates (class 4a of the six classes) | electron microscopy | BD | — | — |
| 4V6P | Structural characterization of mRNA-tRNA translocation intermediates (class 4b of the six classes) | electron microscopy | BD | — | — |
| 4V6Q | Structural characterization of mRNA-tRNA translocation intermediates (class 5 of the six classes) | electron microscopy | BD | — | — |
| 4V6R | Structural characterization of mRNA-tRNA translocation intermediates (class 6 of the six classes) | electron microscopy | BD | — | — |
| 4V6S | Structural characterization of mRNA-tRNA translocation intermediates (class 3 of the six classes) | electron microscopy | AD | — | — |
| 4V6T | Structure of the bacterial ribosome complexed by tmRNA-SmpB and EF-G during translocation and… | electron microscopy | BC | — | — |
| 4V6V | Tetracycline resistance protein Tet(O) bound to the ribosome | electron microscopy | BD | — | — |
216 records more on the page itself.
Ligands
Experiment against prediction
- 7N31 chain LB against the predicted model P60422: TM-score 0.99, RMSD 0.45 Å
- 8QOA chain c against the predicted model P60422: TM-score 0.99, RMSD 0.46 Å
- 8PVA chain c against the predicted model P60422: TM-score 0.99, RMSD 0.46 Å
- 6VYX chain h against the predicted model P60422: TM-score 0.99, RMSD 0.46 Å
- 6VYU chain h against the predicted model P60422: TM-score 0.99, RMSD 0.46 Å
- 6VZ2 chain h against the predicted model P60422: TM-score 0.99, RMSD 0.46 Å
- 6X7F chain h against the predicted model P60422: TM-score 0.99, RMSD 0.46 Å
- 6VYZ chain h against the predicted model P60422: TM-score 0.99, RMSD 0.46 Å
- 6X7K chain h against the predicted model P60422: TM-score 0.99, RMSD 0.46 Å
- 8G6W chain c against the predicted model P60422: TM-score 0.99, RMSD 0.47 Å
Elsewhere
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