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MolNFT v1 · #160873 · protein + DNA

Cryo-EM structure of MLL1 in complex with RBBP5 and WDR5 bound to the nucleosome

6PWW: “Cryo-EM structure of MLL1 in complex with RBBP5 and WDR5 bound to the nucleosome”. Electron microscopy, 1 ligand (ZN). MolNFT v1 #160873 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB
6PWW
Type
protein + DNA
Length
1,842 residues
Chains
13
Method
electron microscopy
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt
Q15291, P61964, Q03164, P84233, P62799, P06897, P02281
Ligands
ZN

Structure

electron microscopy · 9 distinct chains.

ChainMoleculeTypeResiduesSecondary structureUniProt
A—protein333—Q15291
B—protein303—P61964
C—protein154—Q03164
G, K—protein98—P84233
H, L—protein82—P62799
I, M—protein107—P06897
J, N—protein93—P02281
O—dna146——
P—dna146——

Ligands and binding sites

  • ZN · Zinc ion · metal · chains C

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

  • 6PWW · Cryo-EM structure of MLL1 in complex with RbBP5 and WDR5 bound to the nucleosome · the same entry in another collection · chain L against L, TM-score 1.00

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