Research workbench
Cryo-EM structure of MLL1 in complex with RBBP5 and WDR5 bound to the nucleosome
Analyse Cryo-EM structure of MLL1 in complex with RBBP5 and WDR5 bound to the nucleosome in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 6PWW
- Type
- protein + DNA
- Length
- 1,842 residues
- Chains
- 13
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- Q15291, P61964, Q03164, P84233, P62799, P06897, P02281
- Ligands
- ZN
Structure
electron microscopy · 9 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 333 | — | Q15291 |
| B | — | protein | 303 | — | P61964 |
| C | — | protein | 154 | — | Q03164 |
| G, K | — | protein | 98 | — | P84233 |
| H, L | — | protein | 82 | — | P62799 |
| I, M | — | protein | 107 | — | P06897 |
| J, N | — | protein | 93 | — | P02281 |
| O | — | dna | 146 | — | — |
| P | — | dna | 146 | — | — |
Ligands and binding sites
- ZN · Zinc ion · metal · chains C
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 6PWW · Cryo-EM structure of MLL1 in complex with RbBP5 and WDR5 bound to the nucleosome · the same entry in another collection · chain L against L, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q15291
- Every structure of UniProt P61964
- Every structure of UniProt Q03164
- Every structure of UniProt P84233
- Every structure of UniProt P62799
- Every structure of UniProt P06897
- Every structure of UniProt P02281
- Elsewhere: RCSB PDB 6PWW · PDBe 6PWW · UniProt Q15291 · UniProt P61964 · UniProt Q03164 · UniProt P84233 · UniProt P62799 · UniProt P06897 · UniProt P02281
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