Cryo-EM structure of microtubule-bound KIF7 in the ADP state

Structure

electron microscopy · 3 distinct chains.

Ligands and binding sites

• GTP · Guanosine-5'-triphosphate · ligand · chains A, B
• GDP · Guanosine-5'-diphosphate · ligand · chains B
• TA1 · Taxol · ligand · chains B
• ADP · Adenosine-5'-diphosphate · ligand · chains C
• MG · Magnesium ion · metal · 2 copies · chains A, C

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

• 6MLQ · Cryo-EM structure of microtubule-bound Kif7 in the ADP state · the same entry in another collection · chain A against A, TM-score 1.00
• P02550 · AlphaFold monomer V2.0 prediction for tubulin alpha-1A chain (P02550) · a predicted model of the same protein · chain A against A, TM-score 0.95
• Q2M1P5 · AlphaFold monomer V2.0 prediction for kinesin-like protein KIF7 (Q2M1P5) · a predicted model of the same protein · chain C against A, TM-score 0.93

Analyse

• Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
• Every structure of UniProt P02550
• Every structure of UniProt P02554
• Every structure of UniProt Q2M1P5
• Elsewhere: RCSB PDB 6MLQ · PDBe 6MLQ · UniProt P02550 · UniProt P02554 · UniProt Q2M1P5