MolNFT v1 · #146165 · protein
Cryo-EM structure of the human adenosine A1 receptor-GI2-protein complex bound to its endogenous agonist
6D9H: “Cryo-EM structure of the human adenosine A1 receptor-GI2-protein complex bound to its endogenous agonist”. Electron microscopy, 1 ligand (ADN). MolNFT v1 #146165 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6D9H
- Type
- protein
- Length
- 892 residues
- Chains
- 4
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- P04899, P62873, P59768, P08173, P30542
- Ligands
- ADN
Structure
electron microscopy · 4 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 209 | — | P04899 |
| B | — | protein | 338 | — | P62873 |
| G | — | protein | 57 | — | P59768 |
| R | — | protein | 288 | — | P08173, P30542 |
Ligands and binding sites
- ADN · Adenosine · ligand · chains R
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 6D9H · Cryo-EM structure of the human adenosine A1 receptor-Gi2-protein complex bound to its… · the same entry in another collection · chain B against B, TM-score 1.00
- P62873 · AlphaFold monomer V2.0 prediction for guanine nucleotide-binding protein G(I)/G(S)/G(T)… · a predicted model of the same protein · chain B against A, TM-score 0.99
- P59768 · AlphaFold monomer V2.0 prediction for guanine nucleotide-binding protein G(I)/G(S)/G(O)… · a predicted model of the same protein · chain G against A, TM-score 0.93
- P30542 · AlphaFold monomer V2.0 prediction for adenosine receptor A1 (P30542) · a predicted model of the same protein · chain R against A, TM-score 0.92
- P04899 · AlphaFold monomer V2.0 prediction for guanine nucleotide-binding protein G(I) subunit… · a predicted model of the same protein · chain A against A, TM-score 0.83
- P08173 · AlphaFold monomer V2.0 prediction for muscarinic acetylcholine receptor M4 (P08173) · a predicted model of the same protein · chain R against A, TM-score 0.81
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P04899
- Every structure of UniProt P62873
- Every structure of UniProt P59768
- Every structure of UniProt P08173
- Every structure of UniProt P30542
- Elsewhere: RCSB PDB 6D9H · PDBe 6D9H · UniProt P04899 · UniProt P62873 · UniProt P59768 · UniProt P08173 · UniProt P30542
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