UniProt P04899
Guanine nucleotide-binding protein G(i) subunit alpha-2 (P04899)
Guanine nucleotide-binding protein G(i) subunit alpha-2 (UniProt P04899): 16 experimental structures and 1 predicted model on GenesisL1, 48 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P04899
- Protein
- Guanine nucleotide-binding protein G(i) subunit alpha-2
- Experimental structures
- 16
- Predicted models
- 1
- Pockets
- 48 · 7 records with a druggable one
Structures
17 records of P04899 in the MolNFT archive: 16 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6D9H | Cryo-EM structure of the human adenosine A1 receptor-GI2-protein complex bound to its endogenous… | electron microscopy | A | — | — |
| 7F8V | Cryo-EM structure of the cholecystokinin receptor cckbr in complex with gastrin-17 and gi | electron microscopy | A | — | — |
| 7LD3 | Cryo-EM structure of the human adenosine A1 receptor-GI2-protein complex bound to its endogenous… | electron microscopy | A | — | — |
| 7LD4 | Cryo-EM structure of the human adenosine A1 receptor-GI2-protein complex bound to its endogenous… | electron microscopy | A | — | — |
| 7WV9 | Cryo-EM structure of human receptor with G proteins | electron microscopy | A | — | 9 (best 0.84) |
| 7WVV | Cryo-EM structure of the human formyl peptide receptor 2 in complex with fMLFII and Gi2 | electron microscopy | A | — | 4 (best 0.82) |
| 7WVV | Cryo-EM structure of the human formyl peptide receptor 2 in complex with fmlfii and GI2 | electron microscopy | A | — | — |
| 7WVW | Cryo-EM structure of the human formyl peptide receptor 2 in complex with fMYFINILTL and Gi2 | electron microscopy | A | — | — |
| 7WVW | Cryo-EM structure of the human formyl peptide receptor 2 in complex with fmyfiniltl and GI2 | electron microscopy | A | — | — |
| 7WVX | Cryo-EM structure of the human formyl peptide receptor 2 in complex with fhumanin and Gi2 | electron microscopy | A | — | 4 (best 0.83) |
| 7WVX | Cryo-EM structure of the human formyl peptide receptor 2 in complex with fhumanin and GI2 | electron microscopy | A | — | — |
| 7WVY | Cryo-EM structure of the human formyl peptide receptor 2 in complex with ABETA42 and GI2 | electron microscopy | A | — | — |
| 7YK7 | Cryo-EM structure of the DC591053-bound human relaxin family peptide receptor 4 (RXFP4)-Gi complex | electron microscopy | I | — | 7 (best 0.82) |
| 8K6M | Structural complex of neuropeptide Y receptor 1 | electron microscopy | A | — | 10 (best 0.82) |
| 8THK | Cryo-EM structure of A61603-bound alpha-1A-adrenergic receptor in complex with heterotrimeric… | electron microscopy | A | — | 5 (best 0.82) |
| 8ZH8 | Human GPR103 -Gq complex bound to QRFP26 | electron microscopy | A | — | 9 (best 0.82) |
| P04899 | AlphaFold monomer V2.0 prediction for guanine nucleotide-binding protein G(I) subunit alpha-2… | predicted | A | — | — |
Experiment against prediction
- 8ZH8 chain A against the predicted model Q5JWF2: TM-score 0.86, RMSD 2.29 Å
- 7F8V chain A against the predicted model P04899: TM-score 0.84, RMSD 2.84 Å
- 7LD4 chain A against the predicted model P04899: TM-score 0.84, RMSD 2.90 Å
- 7LD3 chain A against the predicted model P04899: TM-score 0.83, RMSD 3.00 Å
- 7WVW chain A against the predicted model P04899: TM-score 0.83, RMSD 2.95 Å
- 7WVW chain A against the predicted model P04899: TM-score 0.83, RMSD 2.95 Å
- 7WVY chain A against the predicted model P04899: TM-score 0.83, RMSD 2.90 Å
- 7WVV chain A against the predicted model P04899: TM-score 0.83, RMSD 2.93 Å
- 7WVV chain A against the predicted model P04899: TM-score 0.83, RMSD 2.93 Å
- 6D9H chain A against the predicted model P04899: TM-score 0.83, RMSD 2.88 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.