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MolNFT v1 · #142974 · protein + DNA + RNA

Cryoem structure of HK022 nun - E.COLI RNA polymerase elongation complex

6ALG: “Cryoem structure of HK022 nun - E.COLI RNA polymerase elongation complex”. Electron microscopy, 2 ligands (ZN, MG). MolNFT v1 #142974 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB
6ALG
Type
protein + DNA + RNA
Length
3,254 residues
Chains
9
Method
electron microscopy
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt
P0A7Z4, P0A8V2, P0A8T7, P0A800, P18683
Ligands
ZN, MG

Structure

electron microscopy · 9 distinct chains.

ChainMoleculeTypeResiduesSecondary structureUniProt
A—dna29——
B—dna29——
R—rna10——
G—protein219—P0A7Z4
H—protein217—P0A7Z4
I—protein1319—P0A8V2
J—protein1335—P0A8T7
K—protein73—P0A800
N—protein23—P18683

Ligands and binding sites

  • ZN · Zinc ion · metal · 2 copies · chains J
  • MG · Magnesium ion · metal · chains R, J

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

  • 6ALG · CryoEM structure of HK022 Nun - E.coli RNA polymerase elongation complex · the same entry in another collection · chain N against N, TM-score 1.00
  • P0A8V2 · AlphaFold monomer V2.0 prediction for DNA-directed RNA polymerase subunit beta (P0A8V2) · a predicted model of the same protein · chain I against A, TM-score 0.99
  • P0A8T7 · AlphaFold monomer V2.0 prediction for DNA-directed RNA polymerase subunit beta' (P0A8T7) · a predicted model of the same protein · chain J against A, TM-score 0.93

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