MolNFT v1 · #388365 · protein
AlphaFold monomer V2.0 prediction for DNA-directed RNA polymerase subunit beta' (P0A8T7)
P0A8T7: “AlphaFold monomer V2.0 prediction for DNA-directed RNA polymerase subunit beta' (P0A8T7)”. 16 pockets (best druggability 0.78). MolNFT v1 #388365 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P0A8T7
- Type
- protein
- Length
- 1,407 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x0EA189b2343A464f560b44103f6A3396Da1dA8a9
- Molecule
- DNA-directed RNA polymerase subunit beta'
- UniProt
- P0A8T7
- Pockets
- 16 · best druggability 0.78
Structure
1 distinct chain · 39% helix, 19% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | DNA-directed RNA polymerase subunit beta' | protein | 1407 | 39% helix, 19% strand | P0A8T7 |
Pockets
16 pockets found on a 1 Å grid, 7 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1074 | 0.78 | 0.80 | 81 | empty |
| 2 | 688 | 0.73 | 0.79 | 54 | empty |
| 3 | 934 | 0.70 | 0.75 | 52 | empty |
| 4 | 630 | 0.70 | 0.77 | 39 | empty |
| 5 | 563 | 0.68 | 0.77 | 50 | empty |
Compared structures
- 6UTW · E. coli sigma-S transcription initiation complex with a 4-nt RNA (Fresh" crystal)" · an experimental structure of the same protein · chain A against DDD, TM-score 0.92
- 6UTV · E. coli sigma-S transcription initiation complex with a 6-nt RNA (Fresh" crystal soaked… · an experimental structure of the same protein · chain A against DDD, TM-score 0.92
- 6UTZ · E. coli sigma-S transcription initiation complex with a 6-nt RNA (Fresh" crystal soaked… · an experimental structure of the same protein · chain A against DDD, TM-score 0.92
- 6UU8 · E. coli mutant sigma-S transcription initiation complex with a 7-nt RNA ("Fresh" mutant… · an experimental structure of the same protein · chain A against DDD, TM-score 0.92
- 6UUA · E. coli sigma-S transcription initiation complex with a mismatching CTP (Fresh" crystal… · an experimental structure of the same protein · chain A against DDD, TM-score 0.92
- 6UTY · E. coli sigma-S transcription initiation complex with a mismatching CTP (Old" crystal… · an experimental structure of the same protein · chain A against DDD, TM-score 0.92
- 5IPM · SigmaS-transcription initiation complex with 4-nt nascent RNA · an experimental structure of the same protein · chain A against D, TM-score 0.92
- 5IPM · Sigmas-transcription initiation complex with 4-nt nascent RNA · an experimental structure of the same protein · chain A against D, TM-score 0.92
- 6UU7 · E. coli sigma-S transcription initiation complex with a 6-nt RNA and an NTP ("Old"… · an experimental structure of the same protein · chain A against DDD, TM-score 0.92
- 6UU5 · E. coli sigma-S transcription initiation complex with a 6-nt RNA ("Old" crystal soaked… · an experimental structure of the same protein · chain A against DDD, TM-score 0.92
- 6UU9 · E. coli mutant sigma-S transcription initiation complex with an 8-nt RNA ("Fresh" mutant… · an experimental structure of the same protein · chain A against DDD, TM-score 0.92
- 5IPN · SigmaS-transcription initiation complex with 4-nt nascent RNA · an experimental structure of the same protein · chain A against D, TM-score 0.92
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P0A8T7
- Elsewhere: UniProt P0A8T7 · AlphaFold DB P0A8T7
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.