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MolNFT v1 · #136048 · protein + DNA + RNA

Crystal structure of mycobacterium tuberculosis transcription initiation complex containing 3 nt of RNA

5UH5: “Crystal structure of mycobacterium tuberculosis transcription initiation complex containing 3 nt of RNA”. X-ray diffraction, 2 ligands (ZN, MG). MolNFT v1 #136048 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB
5UH5
Type
protein + DNA + RNA
Length
3,287 residues
Chains
9
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt
P9WGZ1, P9WGY9, P9WGY7, P9WGY5, P9WGI1
Ligands
ZN, MG

Structure

x-ray diffraction · 9 distinct chains.

ChainMoleculeTypeResiduesSecondary structureUniProt
A—protein224—P9WGZ1
B—protein227—P9WGZ1
C—protein1126—P9WGY9
D—protein1265—P9WGY7
E—protein81—P9WGY5
F—protein322—P9WGI1
H—dna23——
G—dna16——
I—rna3——

Ligands and binding sites

  • ZN · Zinc ion · metal · 2 copies · chains D
  • MG · Magnesium ion · metal · chains D, I

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

  • 5UH5 · Crystal structure of Mycobacterium tuberculosis transcription initiation complex… · the same entry in another collection · chain I against I, TM-score 1.00
  • P9WGY9 · AlphaFold monomer V2.0 prediction for DNA-directed RNA polymerase subunit beta (P9WGY9) · a predicted model of the same protein · chain C against A, TM-score 0.99
  • P9WGY5 · AlphaFold monomer V2.0 prediction for DNA-directed RNA polymerase subunit omega (P9WGY5) · a predicted model of the same protein · chain E against A, TM-score 0.94
  • P9WGZ1 · AlphaFold monomer V2.0 prediction for DNA-directed RNA polymerase subunit alpha (P9WGZ1) · a predicted model of the same protein · chain A against A, TM-score 0.94

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