UniProt P9WGY5
DNA-directed RNA polymerase subunit omega (P9WGY5)
DNA-directed RNA polymerase subunit omega (UniProt P9WGY5), EC 2.7.7.6: 38 experimental structures and 1 predicted model on GenesisL1, 18 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P9WGY5
- Protein
- DNA-directed RNA polymerase subunit omega
- EC
- 2.7.7.6
- Experimental structures
- 38
- Predicted models
- 1
- Pockets
- 18 · 8 records with a druggable one
Structures
39 records of P9WGY5 in the MolNFT archive: 38 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5UH5 | Crystal structure of mycobacterium tuberculosis transcription initiation complex containing 3 nt of… | x-ray diffraction | E | — | — |
| 5UH6 | Crystal structure of mycobacterium tuberculosis transcription initiation complex containing 2NTRNA… | x-ray diffraction | E | — | — |
| 5UH8 | Crystal structure of Mycobacterium tuberculosis transcription initiation complex containing 4nt RNA | x-ray diffraction | E | — | 1 (best 0.74) |
| 5UH8 | Crystal structure of mycobacterium tuberculosis transcription initiation complex containing 4NT RNA | x-ray diffraction | E | — | — |
| 5UH9 | Crystal structure of mycobacterium tuberculosis transcription initiation complex containing 2NT RNA | x-ray diffraction | E | — | — |
| 5UHA | Crystal structure of Mycobacterium tuberculosis transcription initiation complex | x-ray diffraction | E | — | 2 (best 0.74) |
| 5UHA | Crystal structure of mycobacterium tuberculosis transcription initiation complex | x-ray diffraction | E | — | — |
| 5UHB | Crystal structure of mycobacterium tuberculosis transcription initiation complex in complex with… | x-ray diffraction | E | — | — |
| 5UHC | Crystal structure of Mycobacterium tuberculosis transcription initiation complex containing 3nt RNA… | x-ray diffraction | E | — | 3 (best 0.75) |
| 5UHC | Crystal structure of mycobacterium tuberculosis transcription initiation complex containing 3NT RNA… | x-ray diffraction | E | — | — |
| 5UHD | Crystal structure of mycobacterium tuberculosis transcription initiation complex containing 4NT RNA… | x-ray diffraction | E | — | — |
| 5UHE | Crystal structure of mycobacterium tuberculosis transcription initiation complex in complex with… | x-ray diffraction | E | — | — |
| 5UHF | Crystal structure of Mycobacterium tuberculosis transcription initiation complex in complex with… | x-ray diffraction | E | — | 2 (best 0.74) |
| 5UHF | Crystal structure of mycobacterium tuberculosis transcription initiation complex in complex with… | x-ray diffraction | E | — | — |
| 5UHG | Crystal structure of mycobacterium tuberculosis transcription initiation complex in complex with… | x-ray diffraction | E | — | — |
| 5ZX2 | Mycobacterium tuberculosis RNA polymerase transcription initiation complex with ECF sigma factor… | x-ray diffraction | E | — | 2 (best 0.83) |
| 5ZX2 | Mycobacterium tuberculosis RNA polymerase transcription initiation complex with ecf sigma factor… | x-ray diffraction | E | — | — |
| 5ZX3 | Mycobacterium tuberculosis RNA polymerase holoenzyme with ECF sigma factor sigma H | x-ray diffraction | E | — | 3 (best 0.78) |
| 5ZX3 | Mycobacterium tuberculosis RNA polymerase holoenzyme with ecf sigma factor sigma H | x-ray diffraction | E | — | — |
| 6DV9 | Crystal structure of mycobacterium tuberculosis transcription initiation COMPLEX(ECF sigma factor… | x-ray diffraction | E | — | — |
| 6DVB | Crystal structure of Mycobacterium tuberculosis transcription initiation complex(ECF sigma factor… | x-ray diffraction | E | — | — |
| 6DVB | Crystal structure of mycobacterium tuberculosis transcription initiation COMPLEX(ECF sigma factor… | x-ray diffraction | E | — | — |
| 6DVC | Crystal structure of mycobacterium tuberculosis transcription initiation COMPLEX(ECF sigma factor… | x-ray diffraction | E | — | — |
| 6DVD | Crystal structure of Mycobacterium tuberculosis transcription initiation complex(ECF sigma factor… | x-ray diffraction | E | — | — |
| 6DVD | Crystal structure of mycobacterium tuberculosis transcription initiation COMPLEX(ECF sigma factor… | x-ray diffraction | E | — | — |
| 6DVE | Crystal structure of mycobacterium tuberculosis transcription initiation COMPLEX(ECF… | x-ray diffraction | E | — | — |
| 6FBV | Single particle cryo em structure of Mycobacterium tuberculosis RNA polymerase in complex with… | electron microscopy | E | — | 2 (best 0.76) |
| 6FBV | Single particle cryo EM structure of mycobacterium tuberculosis RNA polymerase in complex with… | electron microscopy | E | — | — |
| 6JCX | Mycobacterium tuberculosis transcription initiation complex with ecf sigma factor sigma H and 6NT… | x-ray diffraction | E | — | — |
| 6JCY | Mycobacterium tuberculosis RNA polymerase transcription initiation open complex with a chimeric ecf… | x-ray diffraction | E | — | — |
| 6KON | Mycobacterium tuberculosis initial transcription complex comprising sigma H and 5'-OH RNA of 5 nt | x-ray diffraction | E | — | — |
| 6KON | Mycobacterium tuberculosis initial transcription complex comprising sigma H and 5'-oh RNA of 5 nt | x-ray diffraction | E | — | — |
| 6KOO | Mycobacterium tuberculosis initial transcription complex comprising sigma H and 5'-OH RNA of 7 nt | x-ray diffraction | E | — | — |
| 6KOO | Mycobacterium tuberculosis initial transcription complex comprising sigma H and 5'-oh RNA of 7 nt | x-ray diffraction | E | — | — |
| 6KOP | Mycobacterium tuberculosis initial transcription complex comprising sigma H and 5'-OH RNA of 9 nt | x-ray diffraction | E | — | — |
| 6KOP | Mycobacterium tuberculosis initial transcription complex comprising sigma H and 5'-oh RNA of 9 nt | x-ray diffraction | E | — | — |
| 6KOQ | Mycobacterium tuberculosis initial transcription complex comprising sigma H and 5'-oh RNA of 10 nt | x-ray diffraction | E | — | — |
| 8EOS | M. tuberculosis RNAP elongation complex with NusG and CMPCPP | electron microscopy | E | — | 3 (best 0.75) |
| P9WGY5 | AlphaFold monomer V2.0 prediction for DNA-directed RNA polymerase subunit omega (P9WGY5) | predicted | A | — | — |
Experiment against prediction
- 6JCY chain E against the predicted model P9WGY5: TM-score 0.97, RMSD 0.60 Å
- 6JCX chain E against the predicted model P9WGY5: TM-score 0.97, RMSD 0.57 Å
- 5ZX2 chain E against the predicted model P9WGY5: TM-score 0.96, RMSD 0.62 Å
- 5ZX2 chain E against the predicted model P9WGY5: TM-score 0.96, RMSD 0.62 Å
- 5ZX3 chain E against the predicted model P9WGY5: TM-score 0.96, RMSD 0.66 Å
- 5ZX3 chain E against the predicted model P9WGY5: TM-score 0.96, RMSD 0.66 Å
- 6KON chain E against the predicted model P9WGY5: TM-score 0.95, RMSD 0.73 Å
- 6KON chain E against the predicted model P9WGY5: TM-score 0.95, RMSD 0.73 Å
- 6KOP chain E against the predicted model P9WGY5: TM-score 0.95, RMSD 0.77 Å
- 6KOP chain E against the predicted model P9WGY5: TM-score 0.95, RMSD 0.77 Å
Elsewhere
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