MolNFT v1 · #387427 · protein
AlphaFold monomer V2.0 prediction for DNA-directed RNA polymerase subunit beta (P9WGY9)
P9WGY9: “AlphaFold monomer V2.0 prediction for DNA-directed RNA polymerase subunit beta (P9WGY9)”. 18 pockets (best druggability 0.75). MolNFT v1 #387427 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P9WGY9
- Type
- protein
- Length
- 1,178 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x9073C46348542FfE4327c3F363F9B51B22058e75
- Molecule
- DNA-directed RNA polymerase subunit beta
- UniProt
- P9WGY9
- Pockets
- 18 · best druggability 0.75
Structure
1 distinct chain · 27% helix, 26% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | DNA-directed RNA polymerase subunit beta | protein | 1178 | 27% helix, 26% strand | P9WGY9 |
Pockets
18 pockets found on a 1 Å grid, 5 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 671 | 0.75 | 0.81 | 75 | empty |
| 2 | 74 | 0.72 | 0.97 | 23 | empty |
| 3 | 789 | 0.70 | 0.76 | 72 | empty |
| 4 | 325 | 0.66 | 0.81 | 52 | empty |
| 5 | 263 | 0.65 | 0.82 | 32 | empty |
Compared structures
- 6JCY · Mycobacterium tuberculosis RNA polymerase transcription initiation open complex with a… · an experimental structure of the same protein · chain A against C, TM-score 0.96
- 6JCY · Mycobacterium tuberculosis RNA polymerase transcription initiation open complex with a… · an experimental structure of the same protein · chain A against C, TM-score 0.96
- 6KOP · Mycobacterium tuberculosis initial transcription complex comprising sigma H and 5'-OH RNA… · an experimental structure of the same protein · chain A against C, TM-score 0.96
- 6KOP · Mycobacterium tuberculosis initial transcription complex comprising sigma H and 5'-oh RNA… · an experimental structure of the same protein · chain A against C, TM-score 0.96
- 6KOQ · Mycobacterium tuberculosis initial transcription complex comprising sigma H and 5'-oh RNA… · an experimental structure of the same protein · chain A against C, TM-score 0.96
- 6KOQ · Mycobacterium tuberculosis initial transcription complex comprising sigma H and 5'-OH RNA… · an experimental structure of the same protein · chain A against C, TM-score 0.96
- 6JCX · Mycobacterium tuberculosis transcription initiation complex with ecf sigma factor sigma H… · an experimental structure of the same protein · chain A against C, TM-score 0.95
- 6JCX · Mycobacterium tuberculosis transcription initiation complex with ECF sigma factor sigma H… · an experimental structure of the same protein · chain A against C, TM-score 0.95
- 6KOO · Mycobacterium tuberculosis initial transcription complex comprising sigma H and 5'-oh RNA… · an experimental structure of the same protein · chain A against C, TM-score 0.95
- 6KOO · Mycobacterium tuberculosis initial transcription complex comprising sigma H and 5'-OH RNA… · an experimental structure of the same protein · chain A against C, TM-score 0.95
- 5ZX2 · Mycobacterium tuberculosis RNA polymerase transcription initiation complex with ECF sigma… · an experimental structure of the same protein · chain A against C, TM-score 0.95
- 5ZX2 · Mycobacterium tuberculosis RNA polymerase transcription initiation complex with ecf sigma… · an experimental structure of the same protein · chain A against C, TM-score 0.95
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P9WGY9
- Elsewhere: UniProt P9WGY9 · AlphaFold DB P9WGY9
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