UniProt P9WGY7
DNA-directed RNA polymerase subunit beta' (P9WGY7)
DNA-directed RNA polymerase subunit beta' (UniProt P9WGY7), EC 2.7.7.6: 55 experimental structures on GenesisL1, 6 ligands bound, 350 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- P9WGY7
- Protein
- DNA-directed RNA polymerase subunit beta'
- EC
- 2.7.7.6
- Experimental structures
- 55
- Predicted models
- 0
- Ligands
- 6
- Pockets
- 350 · 23 records with a druggable one
Structures
55 records of P9WGY7 in the MolNFT archive: 55 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5UH5 | Crystal structure of Mycobacterium tuberculosis transcription initiation complex containing 3 nt of… | x-ray diffraction | D | ZN, MG | 16 (best 0.87) |
| 5UH5 | Crystal structure of mycobacterium tuberculosis transcription initiation complex containing 3 nt of… | x-ray diffraction | D | ZN, MG | — |
| 5UH6 | Crystal structure of mycobacterium tuberculosis transcription initiation complex containing 2NTRNA… | x-ray diffraction | D | ZN, MG | — |
| 5UH7 | Crystal structure of beta'MtbSI of Mycobacterium tuberculosis RNA polymerase | x-ray diffraction | A, B | — | 2 (best 0.42) |
| 5UH7 | Crystal structure of BETA'MTBSI of mycobacterium tuberculosis RNA polymerase | x-ray diffraction | A, B | — | — |
| 5UH9 | Crystal structure of Mycobacterium tuberculosis transcription initiation complex containing 2nt RNA | x-ray diffraction | D | ZN, MG | 16 (best 0.83) |
| 5UH9 | Crystal structure of mycobacterium tuberculosis transcription initiation complex containing 2NT RNA | x-ray diffraction | D | ZN, MG | — |
| 5UHA | Crystal structure of Mycobacterium tuberculosis transcription initiation complex | x-ray diffraction | D | ZN, MG | 16 (best 0.84) |
| 5UHA | Crystal structure of mycobacterium tuberculosis transcription initiation complex | x-ray diffraction | D | ZN, MG | — |
| 5UHB | Crystal structure of Mycobacterium tuberculosis transcription initiation complex in complex with… | x-ray diffraction | D | ZN, MG | 17 (best 0.81) |
| 5UHB | Crystal structure of mycobacterium tuberculosis transcription initiation complex in complex with… | x-ray diffraction | D | ZN, MG | — |
| 5UHC | Crystal structure of Mycobacterium tuberculosis transcription initiation complex containing 3nt RNA… | x-ray diffraction | D | ZN, MG | 16 (best 0.83) |
| 5UHC | Crystal structure of mycobacterium tuberculosis transcription initiation complex containing 3NT RNA… | x-ray diffraction | D | ZN, MG | — |
| 5UHD | Crystal structure of Mycobacterium tuberculosis transcription initiation complex containing 4nt RNA… | x-ray diffraction | D | ZN, MG | 16 (best 0.83) |
| 5UHD | Crystal structure of mycobacterium tuberculosis transcription initiation complex containing 4NT RNA… | x-ray diffraction | D | ZN, MG | — |
| 5UHE | Crystal structure of Mycobacterium tuberculosis transcription initiation complex in complex with… | x-ray diffraction | D | ZN, MG, 88G | 18 (best 0.82) |
| 5UHE | Crystal structure of mycobacterium tuberculosis transcription initiation complex in complex with… | x-ray diffraction | D | ZN, MG | — |
| 5UHF | Crystal structure of Mycobacterium tuberculosis transcription initiation complex in complex with… | x-ray diffraction | D | ZN, MG, 88D | 13 (best 0.83) |
| 5UHF | Crystal structure of mycobacterium tuberculosis transcription initiation complex in complex with… | x-ray diffraction | D | ZN, MG | — |
| 5UHG | Crystal structure of Mycobacterium tuberculosis transcription initiation complex in complex with… | x-ray diffraction | D | ZN, MG, 88G | 15 (best 0.83) |
| 5UHG | Crystal structure of mycobacterium tuberculosis transcription initiation complex in complex with… | x-ray diffraction | D | ZN, MG | — |
| 5ZX2 | Mycobacterium tuberculosis RNA polymerase transcription initiation complex with ECF sigma factor… | x-ray diffraction | D | ZN | 13 (best 0.87) |
| 5ZX2 | Mycobacterium tuberculosis RNA polymerase transcription initiation complex with ecf sigma factor… | x-ray diffraction | D | ZN | — |
| 5ZX3 | Mycobacterium tuberculosis RNA polymerase holoenzyme with ECF sigma factor sigma H | x-ray diffraction | D | ZN | 15 (best 0.86) |
| 5ZX3 | Mycobacterium tuberculosis RNA polymerase holoenzyme with ecf sigma factor sigma H | x-ray diffraction | D | ZN | — |
| 6DV9 | Crystal structure of Mycobacterium tuberculosis transcription initiation complex(ECF sigma factor… | x-ray diffraction | D | MG, ZN | 16 (best 0.83) |
| 6DV9 | Crystal structure of mycobacterium tuberculosis transcription initiation COMPLEX(ECF sigma factor… | x-ray diffraction | D | MG, ZN | — |
| 6DVB | Crystal structure of Mycobacterium tuberculosis transcription initiation complex(ECF sigma factor… | x-ray diffraction | D | ZN | — |
| 6DVB | Crystal structure of mycobacterium tuberculosis transcription initiation COMPLEX(ECF sigma factor… | x-ray diffraction | D | ZN | — |
| 6DVC | Crystal structure of mycobacterium tuberculosis transcription initiation COMPLEX(ECF sigma factor… | x-ray diffraction | D | ZN | — |
| 6DVD | Crystal structure of Mycobacterium tuberculosis transcription initiation complex(ECF sigma factor… | x-ray diffraction | D | ZN | — |
| 6DVD | Crystal structure of mycobacterium tuberculosis transcription initiation COMPLEX(ECF sigma factor… | x-ray diffraction | D | ZN | — |
| 6DVE | Crystal structure of mycobacterium tuberculosis transcription initiation COMPLEX(ECF… | x-ray diffraction | D | ZN | — |
| 6FBV | Single particle cryo em structure of Mycobacterium tuberculosis RNA polymerase in complex with… | electron microscopy | D | ZN, MG, FI8 | 14 (best 0.82) |
| 6FBV | Single particle cryo EM structure of mycobacterium tuberculosis RNA polymerase in complex with… | electron microscopy | D | ZN, MG, FI8 | — |
| 6JCX | Mycobacterium tuberculosis transcription initiation complex with ECF sigma factor sigma H and 6nt… | x-ray diffraction | D | ZN, MG | 17 (best 0.85) |
| 6JCX | Mycobacterium tuberculosis transcription initiation complex with ecf sigma factor sigma H and 6NT… | x-ray diffraction | D | ZN, MG | — |
| 6JCY | Mycobacterium tuberculosis RNA polymerase transcription initiation open complex with a chimeric ECF… | x-ray diffraction | D | ZN, MG | 14 (best 0.85) |
| 6JCY | Mycobacterium tuberculosis RNA polymerase transcription initiation open complex with a chimeric ecf… | x-ray diffraction | D | ZN, MG | — |
| 6KON | Mycobacterium tuberculosis initial transcription complex comprising sigma H and 5'-OH RNA of 5 nt | x-ray diffraction | D | ZN, MG | — |
| 6KON | Mycobacterium tuberculosis initial transcription complex comprising sigma H and 5'-oh RNA of 5 nt | x-ray diffraction | D | ZN, MG | — |
| 6KOO | Mycobacterium tuberculosis initial transcription complex comprising sigma H and 5'-OH RNA of 7 nt | x-ray diffraction | D | ZN, MG | — |
| 6KOO | Mycobacterium tuberculosis initial transcription complex comprising sigma H and 5'-oh RNA of 7 nt | x-ray diffraction | D | ZN, MG | — |
| 6KOP | Mycobacterium tuberculosis initial transcription complex comprising sigma H and 5'-OH RNA of 9 nt | x-ray diffraction | D | ZN, MG | — |
| 6KOP | Mycobacterium tuberculosis initial transcription complex comprising sigma H and 5'-oh RNA of 9 nt | x-ray diffraction | D | ZN, MG | — |
| 6KOQ | Mycobacterium tuberculosis initial transcription complex comprising sigma H and 5'-oh RNA of 10 nt | x-ray diffraction | D | ZN, MG | — |
| 7PP4 | Cryo-EM structure of Mycobacterium tuberculosis RNA polymerase holoenzyme comprising sigma factor… | electron microscopy | d | ZN, MG | 14 (best 0.83) |
| 7Q4U | Cryo-EM structure of Mycobacterium tuberculosis RNA polymerase holoenzyme octamer comprising sigma… | electron microscopy | D, J, P, W, CA, IA, OA, UA | ZN, MG | 15 (best 0.82) |
| 7Q59 | Cryo-EM structure of Mycobacterium tuberculosis RNA polymerase holoenzyme dimer comprising sigma… | electron microscopy | D, d | ZN, MG | 14 (best 0.83) |
| 7Z8Q | Cryo-EM structure of Mycobacterium tuberculosis RNA polymerase core | electron microscopy | d | ZN, MG | 12 (best 0.79) |
| 8EHQ | Mycobacterium tuberculosis paused transcription complex with Bacillus subtilis NusG | electron microscopy | D | MG, ZN | 14 (best 0.84) |
| 8EOF | Mycobacterium tuberculosis transcription elongation complex with Bacillus subtilis NusG (EC_PG) | electron microscopy | D | MG, ZN | 15 (best 0.86) |
| 8EOS | M. tuberculosis RNAP elongation complex with NusG and CMPCPP | electron microscopy | D | 2TM, MG, ZN | 17 (best 0.87) |
| 8EOT | M. tuberculosis RNAP elongation complex with NusG | electron microscopy | D | MG, ZN | 15 (best 0.85) |
| P9WGY7 | AlphaFold monomer V2.0 prediction for DNA-directed RNA polymerase subunit beta' (P9WGY7) | — | — | — |
Ligands
- ZN · Zinc ion · in 52 records
- MG · Magnesium ion · in 42 records
- 88G · Nalpha-(benzenecarbonyl)-N-(2-methylphenyl)-D-phenylalaninamide · in 2 records
- FI8 · Fidaxomicin · in 2 records
- 2TM · 5'-O-[(S)-hydroxy{[(s)-hydroxy(phosphonooxy) phosphoryl]methyl}phosphoryl]cytidine · in 1 record
- 88D · N-(2-methylphenyl)-Nalpha-(selenophene-2-carbonyl)-D-phenylalaninamide · in 1 record
Elsewhere
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