UniProt P9WGI1
RNA polymerase sigma factor SigA (P9WGI1)
RNA polymerase sigma factor SigA (UniProt P9WGI1), EC 2.7.7.6: 31 experimental structures on GenesisL1, 5 ligands bound, 81 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- P9WGI1
- Protein
- RNA polymerase sigma factor SigA
- EC
- 2.7.7.6
- Experimental structures
- 31
- Predicted models
- 0
- Ligands
- 5
- Pockets
- 81 · 14 records with a druggable one
Structures
31 records of P9WGI1 in the MolNFT archive: 31 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5UH5 | Crystal structure of Mycobacterium tuberculosis transcription initiation complex containing 3 nt of… | x-ray diffraction | F | — | 5 (best 0.87) |
| 5UH5 | Crystal structure of mycobacterium tuberculosis transcription initiation complex containing 3 nt of… | x-ray diffraction | F | — | — |
| 5UH6 | Crystal structure of mycobacterium tuberculosis transcription initiation complex containing 2NTRNA… | x-ray diffraction | F | RFP | — |
| 5UH8 | Crystal structure of Mycobacterium tuberculosis transcription initiation complex containing 4nt RNA | x-ray diffraction | F | — | 8 (best 0.84) |
| 5UH8 | Crystal structure of mycobacterium tuberculosis transcription initiation complex containing 4NT RNA | x-ray diffraction | F | — | — |
| 5UH9 | Crystal structure of Mycobacterium tuberculosis transcription initiation complex containing 2nt RNA | x-ray diffraction | F | — | 6 (best 0.83) |
| 5UH9 | Crystal structure of mycobacterium tuberculosis transcription initiation complex containing 2NT RNA | x-ray diffraction | F | — | — |
| 5UHA | Crystal structure of Mycobacterium tuberculosis transcription initiation complex | x-ray diffraction | F | — | 6 (best 0.84) |
| 5UHA | Crystal structure of mycobacterium tuberculosis transcription initiation complex | x-ray diffraction | F | — | — |
| 5UHB | Crystal structure of Mycobacterium tuberculosis transcription initiation complex in complex with… | x-ray diffraction | F | — | 4 (best 0.81) |
| 5UHB | Crystal structure of mycobacterium tuberculosis transcription initiation complex in complex with… | x-ray diffraction | F | — | — |
| 5UHC | Crystal structure of Mycobacterium tuberculosis transcription initiation complex containing 3nt RNA… | x-ray diffraction | F | RFP | 6 (best 0.83) |
| 5UHC | Crystal structure of mycobacterium tuberculosis transcription initiation complex containing 3NT RNA… | x-ray diffraction | F | RFP | — |
| 5UHD | Crystal structure of Mycobacterium tuberculosis transcription initiation complex containing 4nt RNA… | x-ray diffraction | F | — | 4 (best 0.80) |
| 5UHD | Crystal structure of mycobacterium tuberculosis transcription initiation complex containing 4NT RNA… | x-ray diffraction | F | — | — |
| 5UHE | Crystal structure of Mycobacterium tuberculosis transcription initiation complex in complex with… | x-ray diffraction | F | — | 6 (best 0.82) |
| 5UHE | Crystal structure of mycobacterium tuberculosis transcription initiation complex in complex with… | x-ray diffraction | F | — | — |
| 5UHF | Crystal structure of Mycobacterium tuberculosis transcription initiation complex in complex with… | x-ray diffraction | F | — | 5 (best 0.81) |
| 5UHF | Crystal structure of mycobacterium tuberculosis transcription initiation complex in complex with… | x-ray diffraction | F | — | — |
| 5UHG | Crystal structure of Mycobacterium tuberculosis transcription initiation complex in complex with… | x-ray diffraction | F | RFP | 6 (best 0.83) |
| 5UHG | Crystal structure of mycobacterium tuberculosis transcription initiation complex in complex with… | x-ray diffraction | F | RFP | — |
| 6FBV | Single particle cryo em structure of Mycobacterium tuberculosis RNA polymerase in complex with… | electron microscopy | F | FI8 | 3 (best 0.77) |
| 6FBV | Single particle cryo EM structure of mycobacterium tuberculosis RNA polymerase in complex with… | electron microscopy | F | FI8 | — |
| 6ONO | Complex structure of WhiB1 and region 4 of SigA in C2221 space group | x-ray diffraction | B, D | SF4 | 2 (best 0.35) |
| 6ONO | Complex structure of WHIB1 and region 4 of siga in C2221 space group | x-ray diffraction | B, D | SF4 | — |
| 6ONU | Complex structure of WhiB1 and region 4 of SigA in P21 space group. | x-ray diffraction | B, D, F, H | SF4 | 7 (best 0.71) |
| 6ONU | Complex structure of WHIB1 and region 4 of siga in P21 space group. | x-ray diffraction | B, D, F, H | SF4 | — |
| 8CWR | Complex structure of WhiB3 and the SigmaAr4-RNAP Beta flap tip chimera in space group R3 | x-ray diffraction | B | SF4, SO4, NI | 1 (best 0.61) |
| 8CWT | Complex structure of WhiB3 and the SigmaAr4-RNAP Beta flap tip chimera in space group P43212 | x-ray diffraction | B, D, F | SF4, NI, SO4 | 9 (best 0.49) |
| 8D5V | WhiB6 bound to the SigmaAr4-RNAP Beta flap tip chimera | x-ray diffraction | B, D | SF4 | 3 (best 0.56) |
| P9WGI1 | AlphaFold monomer V2.0 prediction for RNA polymerase sigma factor siga (P9WGI1) | — | — | — |
Ligands
Experiment against prediction
- 8D5V chain D against the predicted model P9WGY9: TM-score 0.47, RMSD 4.24 Å
- 8D5V chain B against the predicted model P9WGY9: TM-score 0.47, RMSD 4.49 Å
- 8CWR chain B against the predicted model P9WGY9: TM-score 0.40, RMSD 5.22 Å
- 8CWT chain B against the predicted model P9WGY9: TM-score 0.37, RMSD 4.94 Å
- 8CWT chain D against the predicted model P9WGY9: TM-score 0.37, RMSD 4.90 Å
- 8CWT chain F against the predicted model P9WGY9: TM-score 0.36, RMSD 5.10 Å
Elsewhere
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