Research workbench
Crystal structure of a peptide nucleic acid duplex (bt-pna) containing a bicyclic analogue of thymine
Analyse Crystal structure of a peptide nucleic acid duplex (bt-pna) containing a… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 1HZS
- Type
- protein
- Length
- 4 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Peptide nucleic acid
- Ligands
- APN, GPN, OPN, TPN, CPN, NH2
Structure
x-ray diffraction · 1 distinct chain · 0% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B, C, D | Peptide nucleic acid | protein | 1 | 0% helix, 0% strand | — |
Ligands and binding sites
- APN · 2-aminoethylglycine-carbonylmethylene-adenine · ligand · 8 copies · chains B
- GPN · 2-aminoethylglycine-carbonylmethylene-guanine · ligand · 4 copies · chains C
- OPN · {(2-amino-ethyl)-[2-(2-oxo-1,2-dihydro-[1, 8]naphthyridin-3-yl)-acetyl]-amino}-acetic acid · ligand · 4 copies
- TPN · 2-aminoethylglycine-carbonylmethylene-thymine · ligand · 4 copies
- CPN · 2-aminoethylglycine-carbonylmethylene-cytosine · ligand · 4 copies · chains A, B, C, D
- NH2 · Amino group · ion · 4 copies · chains A, B, C, D
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Modifications
Observed in the structure: 4 covalent (covalent ligand).
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Elsewhere: RCSB PDB 1HZS · PDBe 1HZS
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