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Ligand · CPN

CPN · 2-aminoethylglycine-carbonylmethylene-cytosine

CPN, 2-aminoethylglycine-carbonylmethylene-cytosine (C10 H16 N5 O4 +1, 270.3 g/mol), in the MolNFT structures on GenesisL1: bound in 6 records (6 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds most…

Component
CPN
Formula
C10 H16 N5 O4 +1
Class
ligand
Structures
6
PDB entries
6

Binding sites

CPN in 6 structures; the first of them:

  • 176D · NMR solution structure of a peptide nucleic acid complexed with RNA · CPN A4 · binds A8, G9, U10
  • 1HZS · Crystal structure of a peptide nucleic acid duplex (bt-pna) containing a bicyclic… · CPN A6 · binds LYS7
  • 1NR8 · The crystal structure of a D-lysine-based chiral pna-DNA duplex · CPN B9 · binds DG2, DT3
  • 1PDT · PD235, pna-DNA duplex, NMR, 8 structures · CPN B10 · binds DG7, DC8
  • 1PNN · Peptide nucleic acid (pna) complexed with DNA · CPN A1 · binds DG9, DG9
  • 1RRU · The influence of a chiral amino acid on the helical handedness of pna in solution and in… · CPN A1

Residues it binds most

DG 19, DA 13, LYS 5, HIS 4, GLY 3, A 2, DC 2, G 2, DT 1, SER 1 (residue and the binding sites it lines).

Found with

  • TPN · 2-aminoethylglycine-carbonylmethylene-thymine
  • APN · 2-aminoethylglycine-carbonylmethylene-adenine
  • GPN · 2-aminoethylglycine-carbonylmethylene-guanine
  • NH2 · Amino group
  • A66 · 2-aminoethyllysine-carbonylmethylene-adenine
  • C66 · 2-aminoethyllysine-carbonylmethylene-cytosine
  • IPN · 2-aminoethylglycine-carbonylmethylene-5-iodouracil
  • OPN · {(2-amino-ethyl)-[2-(2-oxo-1,2-dihydro-[1, 8]naphthyridin-3-yl)-acetyl]-amino}-acetic acid
  • T66 · 2-aminoethyllysine-carbonylmethylene-thymine
  • MG · Magnesium ion

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