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Ligand · TPN

TPN · 2-aminoethylglycine-carbonylmethylene-thymine

TPN, 2-aminoethylglycine-carbonylmethylene-thymine (C11 H17 N4 O5 +1, 285.3 g/mol), in the MolNFT structures on GenesisL1: bound in 6 records (6 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds most…

Component
TPN
Formula
C11 H17 N4 O5 +1
Class
ligand
Structures
6
PDB entries
6

Binding sites

TPN in 6 structures; the first of them:

  • 176D · NMR solution structure of a peptide nucleic acid complexed with RNA · TPN A5 · binds G7, A8, G9
  • 1HZS · Crystal structure of a peptide nucleic acid duplex (bt-pna) containing a bicyclic… · TPN A4
  • 1NR8 · The crystal structure of a D-lysine-based chiral pna-DNA duplex · TPN B2 · binds DA9, DC10
  • 1PDT · PD235, pna-DNA duplex, NMR, 8 structures · TPN B11 · binds DA6, DG7
  • 1PNN · Peptide nucleic acid (pna) complexed with DNA · TPN A2 · binds DA8, DG9
  • 1RRU · The influence of a chiral amino acid on the helical handedness of pna in solution and in… · TPN A3

Residues it binds most

DA 23, DG 14, DC 2, G 1, A 1, DT 1 (residue and the binding sites it lines).

Found with

  • CPN · 2-aminoethylglycine-carbonylmethylene-cytosine
  • APN · 2-aminoethylglycine-carbonylmethylene-adenine
  • GPN · 2-aminoethylglycine-carbonylmethylene-guanine
  • NH2 · Amino group
  • A66 · 2-aminoethyllysine-carbonylmethylene-adenine
  • C66 · 2-aminoethyllysine-carbonylmethylene-cytosine
  • IPN · 2-aminoethylglycine-carbonylmethylene-5-iodouracil
  • OPN · {(2-amino-ethyl)-[2-(2-oxo-1,2-dihydro-[1, 8]naphthyridin-3-yl)-acetyl]-amino}-acetic acid
  • T66 · 2-aminoethyllysine-carbonylmethylene-thymine
  • MG · Magnesium ion

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