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Ligand · GPN

GPN · 2-aminoethylglycine-carbonylmethylene-guanine

GPN, 2-aminoethylglycine-carbonylmethylene-guanine (C11 H16 N7 O4 +1, 310.3 g/mol), in the MolNFT structures on GenesisL1: bound in 8 records (8 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds most…

Component
GPN
Formula
C11 H16 N7 O4 +1
Class
ligand
Structures
8
PDB entries
8

Binding sites

GPN in 8 structures; the first of them:

  • 176D · NMR solution structure of a peptide nucleic acid complexed with RNA · GPN A1 · binds C12
  • 1HZS · Crystal structure of a peptide nucleic acid duplex (bt-pna) containing a bicyclic… · GPN A1
  • 1NR8 · The crystal structure of a D-lysine-based chiral pna-DNA duplex · GPN B1 · binds DC10
  • 1PDT · PD235, pna-DNA duplex, NMR, 8 structures · GPN B9 · binds DG7, DC8
  • 1QPY · Crystal structure of backbone modified pna hexamer · GPN A2
  • 1RRU · The influence of a chiral amino acid on the helical handedness of pna in solution and in… · GPN A2
  • 3MBS · Crystal structure of 8MER pna · GPN A1001

Residues it binds most

LYS 12, DC 4, DA 1, C 1, DG 1, DT 1 (residue and the binding sites it lines).

Found with

  • APN · 2-aminoethylglycine-carbonylmethylene-adenine
  • CPN · 2-aminoethylglycine-carbonylmethylene-cytosine
  • TPN · 2-aminoethylglycine-carbonylmethylene-thymine
  • NH2 · Amino group
  • EDO · 1,2-ethanediol
  • A66 · 2-aminoethyllysine-carbonylmethylene-adenine
  • C66 · 2-aminoethyllysine-carbonylmethylene-cytosine
  • CP1 · 2-(methylamino)-ethylglycine-carbonylmethylene-cytosine
  • KPN · N-(2-aminoethyl)-N-(2,2'-bipyridin-5-ylacetyl)glycine
  • OPN · {(2-amino-ethyl)-[2-(2-oxo-1,2-dihydro-[1, 8]naphthyridin-3-yl)-acetyl]-amino}-acetic acid
  • T66 · 2-aminoethyllysine-carbonylmethylene-thymine
  • TP1 · 2-(methylamino)-ethylglycine-carbonylmethylene-thymine

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