Research workbench
Structure of a minimal SF3B core in complex with sudemycin D6 (form I)
Analyse Structure of a minimal SF3B core in complex with sudemycin D6 (form I) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 7OMF
- Type
- protein
- Length
- 1,869 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- Q15393, Q9BWJ5, O75533, Q7RTV0
- Ligands
- T2W, ZN, SCN
Structure
x-ray diffraction · 4 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 869 | — | Q15393 |
| B | — | protein | 65 | — | Q9BWJ5 |
| C | — | protein | 842 | — | O75533 |
| D | — | protein | 93 | — | Q7RTV0 |
Ligands and binding sites
- T2W · [(~{Z},2~{S})-5-[[4-[(2~{E},4~{E})-3-methyl-5-[(2~{S}, 4~{R})-4,6,6-trimethyl-4-oxidanyl-oxan-2-yl]penta-2,4-dienyl]cyclohexyl]amino]-5-oxidanylidene-pent-3-en-2-yl] ~{N}-methylcarbamate · ligand · chains C, D
- ZN · Zinc ion · metal · 3 copies · chains D
- SCN · Thiocyanate ion · ion · chains D
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- Q15393 · AlphaFold monomer V2.0 prediction for splicing factor 3B subunit 3 (Q15393) · a predicted model of the same protein · chain A against A, TM-score 0.99
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q15393
- Every structure of UniProt Q9BWJ5
- Every structure of UniProt O75533
- Every structure of UniProt Q7RTV0
- Elsewhere: RCSB PDB 7OMF · PDBe 7OMF · UniProt Q15393 · UniProt Q9BWJ5 · UniProt O75533 · UniProt Q7RTV0
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