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Cryo-EM structure of the activated glucagon-like peptide-1 receptor in complex with G protein

Analyse Cryo-EM structure of the activated glucagon-like peptide-1 receptor in complex… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB
5VAI
Type
protein
Length
1,178 residues
Chains
6
Method
electron microscopy
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt
G1SGD4, P01275, P63092, P54311, P63212

Structure

electron microscopy · 6 distinct chains.

ChainMoleculeTypeResiduesSecondary structureUniProt
R—protein387—G1SGD4
P—protein31—P01275
A—protein234—P63092
B—protein340—P54311
G—protein58—P63212
N—protein128——

Compared structures

  • 5VAI · Cryo-EM structure of the activated Glucagon-like peptide-1 receptor in complex with G… · the same entry in another collection · chain N against N, TM-score 1.00
  • P54311 · AlphaFold monomer V2.0 prediction for guanine nucleotide-binding protein G(I)/G(S)/G(T)… · a predicted model of the same protein · chain B against A, TM-score 0.98
  • P63092 · AlphaFold monomer V2.0 prediction for guanine nucleotide-binding protein G(S) subunit… · a predicted model of the same protein · chain A against A, TM-score 0.81
  • P01275 · AlphaFold monomer V2.0 prediction for pro-glucagon (P01275) · a predicted model of the same protein · chain P against A, TM-score 0.73
  • P63212 · AlphaFold monomer V2.0 prediction for guanine nucleotide-binding protein G(I)/G(S)/G(O)… · a predicted model of the same protein · chain G against A, TM-score 0.61

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