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AlphaFold monomer V2.0 prediction for prestin (Q9EPH0)

Analyse AlphaFold monomer V2.0 prediction for prestin (Q9EPH0) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

Accession
Q9EPH0
Type
protein
Length
744 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0xeB1fc2b3A6E88e205A4Dd4Dca5DD00c4247413E8
Molecule
Prestin
UniProt
Q9EPH0
Pockets
7 · best druggability 0.74

Structure

1 distinct chain · 62% helix, 5% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
APrestinprotein74462% helix, 5% strandQ9EPH0

Pockets

7 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
11610.740.9137empty
24790.710.8148empty
33500.590.7733empty
43320.580.7733empty
51200.440.7723empty

Compared structures

  • 3LLO · Crystal structure of the STAS domain of motor protein prestin (anion transporter SLC26A5) · an experimental structure of the same protein · chain A against A, TM-score 0.17
  • 3LLO · Crystal structure of the stas domain of motor protein prestin (anion transporter SLC26A5) · an experimental structure of the same protein · chain A against A, TM-score 0.17
  • 5EUZ · Rat prestin STAS domain in complex with iodide · an experimental structure of the same protein · chain A against A, TM-score 0.17
  • 5EUZ · Rat prestin stas domain in complex with iodide · an experimental structure of the same protein · chain A against A, TM-score 0.17
  • 5EUX · Rat prestin stas domain in complex with thiocyanate · an experimental structure of the same protein · chain A against A, TM-score 0.17
  • 5EUX · Rat prestin STAS domain in complex with thiocyanate · an experimental structure of the same protein · chain A against A, TM-score 0.17
  • 5EUW · Rat prestin stas domain in complex with nitrate · an experimental structure of the same protein · chain A against A, TM-score 0.17
  • 5EUW · Rat prestin STAS domain in complex with nitrate · an experimental structure of the same protein · chain A against A, TM-score 0.17
  • 5EUS · Rat prestin STAS domain in complex with bromide · an experimental structure of the same protein · chain A against A, TM-score 0.17
  • 5EUS · Rat prestin stas domain in complex with bromide · an experimental structure of the same protein · chain A against A, TM-score 0.17
  • 5EUU · Rat prestin STAS domain in complex with chloride · an experimental structure of the same protein · chain A against A, TM-score 0.17
  • 5EUU · Rat prestin stas domain in complex with chloride · an experimental structure of the same protein · chain A against A, TM-score 0.17

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