MolNFT v1 · #118204 · protein

Rat prestin stas domain in complex with chloride

5EUU · PRESTIN,PRESTIN: “Rat prestin stas domain in complex with chloride”. X-ray diffraction, 1 ligand (CL), 1 pocket (best druggability 0.61). MolNFT v1 #118204 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 5EUU
Type: protein
Length: 129 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: PRESTIN,PRESTIN
UniProt: Q9EPH0
Ligands: CL
Pockets: 1 · best druggability 0.61

Structure

x-ray diffraction · 1 distinct chain · 35% helix, 22% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	PRESTIN,PRESTIN	protein	129	35% helix, 22% strand	Q9EPH0

Ligands and binding sites

CL · Chloride ion · ion · 2 copies · chains A
EDO · 1,2-ethanediol · additive · 3 copies · chains A
PG4 · Tetraethylene glycol · additive · chains A
PGE · Triethylene glycol · additive · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	68	0.61	0.90	15	empty

Compared structures

5EUU · Rat prestin STAS domain in complex with chloride · the same entry in another collection · chain A against A, TM-score 1.00
Q9EPH0 · AlphaFold monomer V2.0 prediction for prestin (Q9EPH0) · a predicted model of the same protein · chain A against A, TM-score 0.92

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9EPH0
Elsewhere: RCSB PDB 5EUU · PDBe 5EUU · UniProt Q9EPH0

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