MolNFT v1 · #118209 · protein
Rat prestin stas domain in complex with iodide
5EUZ · PRESTIN,PRESTIN: “Rat prestin stas domain in complex with iodide”. X-ray diffraction, 1 ligand (IOD), 3 pockets (best druggability 0.61). MolNFT v1 #118209 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 5EUZ
- Type
- protein
- Length
- 130 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- PRESTIN,PRESTIN
- UniProt
- Q9EPH0
- Ligands
- IOD
- Pockets
- 3 · best druggability 0.61
Structure
x-ray diffraction · 1 distinct chain · 35% helix, 22% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | PRESTIN,PRESTIN | protein | 130 | 35% helix, 22% strand | Q9EPH0 |
Ligands and binding sites
- IOD · Iodide ion · ion · 4 copies · chains A
- EDO · 1,2-ethanediol · additive · 5 copies · chains A
- PEG · Di(hydroxyethyl)ether · additive · 2 copies · chains A
- PGE · Triethylene glycol · additive · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 67 | 0.61 | 0.90 | 14 | empty |
| 2 | 51 | 0.39 | 0.81 | 14 | IOD |
| 3 | 64 | 0.29 | 0.74 | 13 | IOD, PGE |
Modifications
Observed in the structure: 1 modified (engineered).
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9EPH0
- Elsewhere: RCSB PDB 5EUZ · PDBe 5EUZ · UniProt Q9EPH0
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