Research workbench
AlphaFold monomer V2.0 prediction for runt-related transcription factor 2 (Q13950)
Analyse AlphaFold monomer V2.0 prediction for runt-related transcription factor 2… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- Accession
- Q13950
- Type
- protein
- Length
- 521 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xc0F878C3f3E2a1874e2A6daC80d429e553DdB0D5
- Molecule
- Runt-related transcription factor 2
- UniProt
- Q13950
- Pockets
- 1 · best druggability 0.34
Structure
1 distinct chain · 12% helix, 10% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Runt-related transcription factor 2 | protein | 521 | 12% helix, 10% strand | Q13950 |
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 85 | 0.34 | 0.74 | 14 | empty |
Compared structures
- 6VG8 · Crystal structure of the DNA binding domains of human FLI1 and Runx2 in complex with… · an experimental structure of the same protein · chain A against D, TM-score 0.23
- 6VG8 · Crystal structure of the DNA binding domains of human FLI1 and RUNX2 in complex with… · an experimental structure of the same protein · chain A against D, TM-score 0.23
- 6VGG · Crystal structure of the DNA binding domains of human transcription factor erg, human… · an experimental structure of the same protein · chain A against D, TM-score 0.22
- 6VGG · Crystal structure of the DNA binding domains of human transcription factor ERG, human… · an experimental structure of the same protein · chain A against D, TM-score 0.22
- 6VGE · Crystal structure of the DNA binding domains of human transcription factor ERG, human… · an experimental structure of the same protein · chain A against D, TM-score 0.22
- 6VGE · Crystal structure of the DNA binding domains of human transcription factor erg, human… · an experimental structure of the same protein · chain A against D, TM-score 0.22
- 6VGD · Crystal structure of the DNA binding domain (dbd) of human FLI1 and the complex of the… · an experimental structure of the same protein · chain A against D, TM-score 0.22
- 6VGD · Crystal structure of the DNA binding domain (DBD) of human FLI1 and the complex of the… · an experimental structure of the same protein · chain A against D, TM-score 0.22
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q13950
- Elsewhere: UniProt Q13950 · AlphaFold DB Q13950
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