UniProt Q13950
Runt-related transcription factor 2 (Q13950)
Runt-related transcription factor 2 (UniProt Q13950): 6 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 7 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q13950
- Protein
- Runt-related transcription factor 2
- Experimental structures
- 6
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 7 · 1 record with a druggable one
Structures
7 records of Q13950 in the MolNFT archive: 6 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6VG8 | Crystal structure of the DNA binding domains of human FLI1 and RUNX2 in complex with 16-mer DNA… | x-ray diffraction | D | — | — |
| 6VGD | Crystal structure of the DNA binding domain (DBD) of human FLI1 and the complex of the DBD of human… | x-ray diffraction | D | — | 6 (best 0.72) |
| 6VGD | Crystal structure of the DNA binding domain (dbd) of human FLI1 and the complex of the dbd of human… | x-ray diffraction | D | — | — |
| 6VGE | Crystal structure of the DNA binding domains of human transcription factor erg, human RUNX2 bound… | x-ray diffraction | D | — | — |
| 6VGG | Crystal structure of the DNA binding domains of human transcription factor ERG, human Runx2 bound… | x-ray diffraction | D | QWP | — |
| 6VGG | Crystal structure of the DNA binding domains of human transcription factor erg, human RUNX2 bound… | x-ray diffraction | D | QWP | — |
| Q13950 | AlphaFold monomer V2.0 prediction for runt-related transcription factor 2 (Q13950) | predicted | A | — | 1 (best 0.34) |
Ligands
- QWP · mithramycin · in 2 records
Experiment against prediction
- 6VGG chain D against the predicted model Q13950: TM-score 0.97, RMSD 0.83 Å
- 6VGG chain D against the predicted model Q13950: TM-score 0.97, RMSD 0.83 Å
- 6VGE chain D against the predicted model Q13950: TM-score 0.97, RMSD 0.85 Å
- 6VGD chain D against the predicted model Q13950: TM-score 0.97, RMSD 0.85 Å
- 6VGD chain D against the predicted model Q13950: TM-score 0.97, RMSD 0.85 Å
- 6VG8 chain D against the predicted model Q13950: TM-score 0.96, RMSD 0.87 Å
Elsewhere
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