Research workbench
AlphaFold monomer V2.0 prediction for SERINE/THREONINE-protein kinase RIO1 (Q9BRS2)
Analyse AlphaFold monomer V2.0 prediction for SERINE/THREONINE-protein kinase RIO1… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- Accession
- Q9BRS2
- Type
- protein
- Length
- 568 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x883C20F15F12833b6C5517ea6E586FFca13021dB
- Molecule
- SERINE/THREONINE-protein kinase RIO1
- UniProt
- Q9BRS2
- Pockets
- 7 · best druggability 0.72
Structure
1 distinct chain · 40% helix, 10% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | SERINE/THREONINE-protein kinase RIO1 | protein | 568 | 40% helix, 10% strand | Q9BRS2 |
Pockets
7 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 667 | 0.72 | 0.79 | 60 | empty |
| 2 | 375 | 0.70 | 0.82 | 53 | empty |
| 3 | 241 | 0.53 | 0.76 | 28 | empty |
| 4 | 176 | 0.51 | 0.78 | 20 | empty |
| 5 | 138 | 0.48 | 0.78 | 22 | empty |
Compared structures
- 6ZXF · Cryo-EM structure of a late human pre-40S ribosomal subunit - state G · an experimental structure of the same protein · chain A against z, TM-score 0.54
- 6ZXF · Cryo-EM structure of a late human pre-40S ribosomal subunit - State G · an experimental structure of the same protein · chain A against z, TM-score 0.54
- 6ZXG · Cryo-EM structure of a late human pre-40S ribosomal subunit - State H1 · an experimental structure of the same protein · chain A against z, TM-score 0.49
- 6ZXG · Cryo-EM structure of a late human pre-40S ribosomal subunit - state H1 · an experimental structure of the same protein · chain A against z, TM-score 0.49
- 6ZXH · Cryo-EM structure of a late human pre-40S ribosomal subunit - state H2 · an experimental structure of the same protein · chain A against z, TM-score 0.49
- 6ZXH · Cryo-EM structure of a late human pre-40S ribosomal subunit - State H2 · an experimental structure of the same protein · chain A against z, TM-score 0.49
- 6ZXD · Cryo-EM structure of a late human pre-40S ribosomal subunit - state F1 · an experimental structure of the same protein · chain A against z, TM-score 0.45
- 6ZXD · Cryo-EM structure of a late human pre-40S ribosomal subunit - State F1 · an experimental structure of the same protein · chain A against z, TM-score 0.45
- 4OTP · Crystal structure of the catalytic domain of the human RioK1 atypical protein kinase in… · an experimental structure of the same protein · chain A against A, TM-score 0.41
- 4OTP · Crystal structure of the catalytic domain of the human RIOK1 atypical protein kinase in… · an experimental structure of the same protein · chain A against A, TM-score 0.41
- 6ZXE · Cryo-EM structure of a late human pre-40S ribosomal subunit - state F2 · an experimental structure of the same protein · chain A against z, TM-score 0.41
- 6ZXE · Cryo-EM structure of a late human pre-40S ribosomal subunit - State F2 · an experimental structure of the same protein · chain A against z, TM-score 0.41
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9BRS2
- Elsewhere: UniProt Q9BRS2 · AlphaFold DB Q9BRS2
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