UniProt Q9VUL1
CTP synthase (Q9VUL1)
CTP synthase (UniProt Q9VUL1), EC 6.3.4.2: 13 experimental structures on GenesisL1, 13 ligands bound, 140 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- Q9VUL1
- Protein
- CTP synthase
- EC
- 6.3.4.2
- Experimental structures
- 13
- Predicted models
- 0
- Ligands
- 13
- Pockets
- 140 · 8 records with a druggable one
Structures
13 records of Q9VUL1 in the MolNFT archive: 13 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6L6Z | Cryo-EM structure of the Drosophila CTP synthase substrate-bound filament | electron microscopy | D, A, B, C, H, E, F, G | — | 20 (best 0.86) |
| 6L6Z | Cryo-EM structure of the drosophila CTP synthase substrate-bound filament | electron microscopy | D, A, B, C, H, E, F, G | — | — |
| 6LFG | Cryo-EM structure of the Drosophila CTP synthase product-bound filament | electron microscopy | D, A, B, C, E, F, G, H | — | 20 (best 0.89) |
| 6LFG | Cryo-EM structure of the drosophila CTP synthase product-bound filament | electron microscopy | D, A, B, C, E, F, G, H | — | — |
| 7DPT | Structural basis for ligand binding modes of CTP synthase | electron microscopy | A, B, C, D | GTP, DON, ADP, MG, 5ZL | 16 (best 0.85) |
| 7DPT | Structural basis for ligand binding modes of CTP synthase | electron microscopy | A, B, C, D | GTP, ADP, MG, 5ZL | — |
| 7DPW | Structural basis for ligand binding modes of CTP synthase | electron microscopy | A, B, C, D | CTP, MG | 19 (best 0.87) |
| 7DPW | Structural basis for ligand binding modes of CTP synthase | electron microscopy | A, B, C, D | CTP | — |
| 7WIZ | Structural basis for ligand binding modes of CTP synthase | electron microscopy | A, B, C, D | GLN, ACP, UTP | 20 (best 0.79) |
| 7WJ4 | Structural basis for ligand binding modes of CTP synthase | electron microscopy | D, A, B, C | GTP, ATP, GGL, MG, UTP | 20 (best 0.79) |
| 9IZ1 | dmCTPS tetramer with dATP dUTP dGTP and DON | electron microscopy | A, B, C, D | DON, MG, DAT, DGT, 5ZL | 20 (best 0.83) |
| 9IZ2 | Focus refinement dmCTPS bound with dATP dUTP dGTP and DON | electron microscopy | A, B, C | DON, MG, DAT, DGT, 5ZL | 5 (best 0.81) |
| Q9VUL1 | AlphaFold monomer V2.0 prediction for CTP synthase (Q9VUL1) | — | — | — |
Ligands
- MG · Magnesium ion · in 6 records
- 5ZL · [[(2~{R},3~{S},4~{R},5~{R})-3,4-bis(oxidanyl)-5-(2-oxidanyl-4-phosphonooxy-pyrimidin-1-yl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] phosphono hydrogen phosphate · in 4 records
- DON · 6-diazenyl-5-oxo-L-norleucine · in 3 records
- GTP · Guanosine-5'-triphosphate · in 3 records
- ADP · Adenosine-5'-diphosphate · in 2 records
- CTP · Cytidine-5'-triphosphate · in 2 records
- DAT · 2'-deoxyadenosine-5'-diphosphate · in 2 records
- DGT · 2'-deoxyguanosine-5'-triphosphate · in 2 records
- UTP · Uridine 5'-triphosphate · in 2 records
- ACP · Phosphomethylphosphonic acid adenylate ester · in 1 record
- ATP · Adenosine-5'-triphosphate · in 1 record
- GGL · Gamma-L-glutamic acid · in 1 record
- GLN · Glutamine · in 1 record
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.