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Ligand · 5ZL

5ZL · [[(2~{R},3~{S},4~{R},5~{R})-3,4-bis(oxidanyl)-5-(2-oxidanyl-4-phosphonooxy-pyrimidin-1-yl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] phosphono hydrogen phosphate

5ZL, [[(2~{R},3~{S},4~{R},5~{R})-3,4-bis(oxidanyl)-5-(2-oxidanyl-4-phosphonooxy-pyrimidin-1-yl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] phosphono hydrogen phosphate (C9 H17 N2 O18 P4 +1, 565.1 g/mol), in the MolNFT structures on GenesisL1…

Component
5ZL
Formula
C9 H17 N2 O18 P4 +1
Class
ligand
Structures
4
PDB entries
3

Binding sites

5ZL in 4 structures; the first of them:

  • 7DPT · Structural basis for ligand binding modes of CTP synthase · 5ZL A708 · binds SER12, GLY13, LYS16, LYS38, ASP40, PRO41, TYR42, HIS55 and 15 more
  • 9IZ1 · dmCTPS tetramer with dATP dUTP dGTP and DON · 5ZL A607 · binds SER12, LYS16, LYS38, ASP40, PRO41, TYR42, HIS55, ASP68 and 14 more
  • 9IZ2 · Focus refinement dmCTPS bound with dATP dUTP dGTP and DON · 5ZL A607 · binds SER12, LYS16, LYS38, ASP40, PRO41, TYR42, HIS55, ASP68 and 15 more
  • 7DPT · Structural basis for ligand binding modes of CTP synthase · 5ZL A708 · binds SER12, GLY13, LYS16, LYS38, ASP40, PRO41, TYR42, HIS55 and 15 more

Residues it binds most

LYS 13, ASP 13, GLY 13, GLN 13, GLU 13, PRO 13, THR 13, HIS 13, SER 13, TYR 13 (residue and the binding sites it lines).

Found with

  • DON · 6-diazenyl-5-oxo-L-norleucine
  • MG · Magnesium ion
  • ADP · Adenosine-5'-diphosphate
  • DAT · 2'-deoxyadenosine-5'-diphosphate
  • DGT · 2'-deoxyguanosine-5'-triphosphate
  • GTP · Guanosine-5'-triphosphate

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