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Ligand · GGL

GGL · Gamma-L-glutamic acid

GGL, Gamma-L-glutamic acid (C5 H9 N O4, 147.1 g/mol), in the MolNFT structures on GenesisL1: bound in 17 records (17 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds most and the ligands found with it.

Component
GGL
Formula
C5 H9 N O4
Class
ligand
Structures
17
PDB entries
17

Binding sites

GGL in 17 structures; the first of them:

  • 2M5P · Solution structure of lipidated glucagon analog in water · GGL X101 · binds LYS12, LYS13, LEU14, ARG17
  • 2M5Q · Solution structure of lipidated glucagon analog in d-TFE · GGL X101 · binds ASP9, TYR10, LYS13
  • 7F5X · GK domain of Drosophila P5CS filament with glutamate · GGL A801 · binds THR102, SER103, GLY104, ALA105, VAL106, ASN204, THR205, ASP207 and 1 more
  • 7FIN · Cryo-EM structure of the GIPR/GLP-1R/GCGR triagonist peptide 20-bound human GIPR-Gs… · GGL P501 · binds GLU135, GLN138, LYS10
  • 7WJ4 · Structural basis for ligand binding modes of CTP synthase · GGL D703 · binds GLY371, GLY372, PHE373, ILE398, CYS399, LEU400, GLN403, ARG479 and 4 more
  • 8J0G · GK monomer complexes with glutamate and ATP · GGL B802 · binds THR23, SER59, SER60, GLY61, ALA62, VAL63, GLN100, ASN154 and 6 more
  • 8XCP · Cryo-EM structure of Glutamate dehydrogenase from Thermococcus profundus incorporating… · GGL A501 · binds LYS69, GLY70, GLY71, MET90, LYS93, LYS105, ALA143, PRO144 and 5 more
  • 8XCQ · Cryo-EM structure of Glutamate dehydrogenase from Thermococcus profundus incorporating… · GGL A501 · binds LYS69, GLY70, GLY71, MET90, LYS93, LYS105, ALA143, PRO144 and 5 more
  • 8XCR · Cryo-EM structure of Glutamate dehydrogenase from Thermococcus profundus in complex with… · GGL A501 · binds LYS69, GLY70, GLY71, MET90, LYS93, LYS105, ALA143, PRO144 and 7 more
  • 8XCU · Cryo-EM structure of Glutamate dehydrogenase from Thermococcus profundus incorporating… · GGL A502 · binds LYS69, GLY70, GLY71, MET90, LYS93, LYS105, ALA143, PRO144 and 4 more
  • 8XCX · Cryo-EM structure of Glutamate dehydrogenase from Thermococcus profundus incorporating… · GGL A501 · binds LYS69, GLY70, GLY71, MET90, LYS93, LYS105, ALA143, PRO144 and 4 more
  • 8XCY · Cryo-EM structure of Glutamate dehydrogenase from Thermococcus profundus incorporating… · GGL A501 · binds LYS69, GLY71, MET90, LYS93, LYS105, ALA143, PRO144, ASP145 and 3 more
  • 8XCZ · Cryo-EM structure of glutamate dehydrogenase from thermococcus profundus incorporating… · GGL A501 · binds LYS69, GLY70, GLY71, MET90, LYS93, LYS105, ALA143, ASN319 and 3 more
  • 8XD2 · Cryo-EM structure of Glutamate dehydrogenase from Thermococcus profundus incorporating… · GGL A502 · binds ALA295, ALA296, VAL317, ALA318, ASN319, ASN344
  • 8XD3 · Cryo-EM structure of Glutamate dehydrogenase from Thermococcus profundus incorporating… · GGL A501 · binds LYS69, GLY70, GLY71, MET90, LYS93, LYS105, ALA143, PRO144 and 5 more
  • 8XD4 · Cryo-EM structure of Glutamate dehydrogenase from Thermococcus profundus incorporating… · GGL A501 · binds ALA223, ALA295, ALA296, VAL317, ALA318, ASN319, ASN344
  • 8XD5 · Cryo-EM structure of Glutamate dehydrogenase from Thermococcus profundus in complex with… · GGL A501 · binds LYS69, GLY70, GLY71, MET90, LYS93, LYS105, ALA143, PRO144 and 8 more

Residues it binds most

GLY 19, LYS 14, ALA 17, ASN 11, THR 13, VAL 17, ASP 15, SER 15, ARG 10, MET 9 (residue and the binding sites it lines).

Found with

  • NAP · Nadp nicotinamide-adenine-dinucleotide phosphate
  • ATP · Adenosine-5'-triphosphate
  • PLM · Palmitic acid
  • MG · Magnesium ion
  • AKG · 2-oxoglutaric acid
  • CLR · Cholesterol
  • GTP · Guanosine-5'-triphosphate
  • NDP · Nadph dihydro-nicotinamide-adenine-dinucleotide phosphate
  • UTP · Uridine 5'-triphosphate

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