UniProt Q9UXG1
Minichromosome maintenance protein MCM (Q9UXG1)
Minichromosome maintenance protein MCM (UniProt Q9UXG1), EC 3.6.4.12: 21 experimental structures and 1 predicted model on GenesisL1, 4 ligands bound, 169 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- Q9UXG1
- Protein
- Minichromosome maintenance protein MCM
- EC
- 3.6.4.12
- Experimental structures
- 21
- Predicted models
- 1
- Ligands
- 4
- Pockets
- 169 · 9 records with a druggable one
Structures
22 records of Q9UXG1 in the MolNFT archive: 21 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2M45 | NMR solution structure of the C-terminus of the minichromosome maintenance protein MCM from… | solution nmr | A | — | — |
| 2M45 | NMR solution structure of the C-terminus of the minichromosome maintenance protein mcm from… | solution nmr | A | — | — |
| 2VL6 | Structural analysis of the sulfolobus solfataricus mcm protein N- terminal domain | x-ray diffraction | A, B, C | — | — |
| 2VL6 | Structural analysis of the sulfolobus solfataricus mcm protein N-terminal domain | x-ray diffraction | A, B, C | — | — |
| 3F9V | Crystal Structure Of A Near Full-Length Archaeal MCM: Functional Insights For An AAA+ Hexameric… | x-ray diffraction | A | — | — |
| 3F9V | Crystal structure of a near full-length archaeal mcm: functional insights for an aaa+ hexameric… | x-ray diffraction | A | — | — |
| 4FDG | Crystal Structure of an Archaeal MCM Filament | x-ray diffraction | B, A, C, D, E | — | — |
| 4FDG | Crystal structure of an archaeal mcm filament | x-ray diffraction | B, A, C, D, E | — | — |
| 4R7Y | Crystal structure of an active MCM hexamer | x-ray diffraction | A, B | — | — |
| 4R7Y | Crystal structure of an active mcm hexamer | x-ray diffraction | A, B | — | — |
| 6MII | Crystal structure of minichromosome maintenance protein MCM/DNA complex | x-ray diffraction | A, B, C, D, E, F | 08T, ZN, MG, ADP | 20 (best 0.85) |
| 6MII | Crystal structure of minichromosome maintenance protein MCM/DNA complex | x-ray diffraction | A, B, C, D, E, F | 08T, ZN, MG, ADP | — |
| 6WNZ | Structure of a dimer of the sulfolobus solfataricus mcm N-terminal domain reveals potential role in… | x-ray diffraction | B, A | ZN | — |
| 8EAF | SsoMCM hexamer bound to Mg/ADP-BeFx and 12-mer oligo-dT. Class 1 | electron microscopy | A, B, C, D, E, F | ZN, MG, 08T | 20 (best 0.86) |
| 8EAG | SsoMCM hexamer bound to Mg/ADP-BeFx and 12-mer oligo-dT. Class 2 | electron microscopy | A, B, C, D, E, F | ZN, MG, 08T | 20 (best 0.87) |
| 8EAH | SsoMCM hexamer bound to Mg/ADP-BeFx and 16-mer oligo-dT. Class 1 | electron microscopy | A, B, C, D, E, F | ZN, MG, 08T | 20 (best 0.86) |
| 8EAI | SsoMCM hexamer bound to Mg/ADP-BeFx and 16-mer oligo-dT. Class 2 | electron microscopy | A, B, C, D, E, F | ZN, MG, 08T | — |
| 8EAJ | SsoMCM hexamer bound to Mg/ADP-BeFx and 46-mer DNA strand. Class 1 | electron microscopy | A, B, C, D, E, F | ZN, MG, 08T | 20 (best 0.86) |
| 8EAK | SsoMCM hexamer bound to Mg/ADP-BeFx and 46-mer DNA strand. Class 2 | electron microscopy | A, B, C, D, E, F | ZN, MG, 08T | 20 (best 0.85) |
| 8EAL | SsoMCM hexamer bound to Mg/ADP-BeFx and DNA. Class 1. Merged particles from datasets with 3… | electron microscopy | A, B, C, D, E, F | ZN, MG, 08T | 20 (best 0.87) |
| 8EAM | SsoMCM hexamer bound to Mg/ADP-BeFx and DNA. Class 2. Merged particles from datasets with 3… | electron microscopy | A, B, C, D, E, F | ZN, MG, 08T | 20 (best 0.83) |
| Q9UXG1 | AlphaFold monomer V2.0 prediction for minichromosome maintenance protein mcm (Q9UXG1) | predicted | A | — | 9 (best 0.66) |
Ligands
Experiment against prediction
- 2VL6 chain A against the predicted model Q9UXG1: TM-score 0.94, RMSD 1.66 Å
- 2VL6 chain A against the predicted model Q9UXG1: TM-score 0.94, RMSD 1.66 Å
- 8EAG chain A against the predicted model Q9UXG1: TM-score 0.92, RMSD 1.51 Å
- 8EAK chain A against the predicted model Q9UXG1: TM-score 0.92, RMSD 1.56 Å
- 8EAI chain A against the predicted model Q9UXG1: TM-score 0.92, RMSD 1.54 Å
- 8EAM chain A against the predicted model Q9UXG1: TM-score 0.92, RMSD 1.55 Å
- 4FDG chain B against the predicted model Q9UXG1: TM-score 0.89, RMSD 3.07 Å
- 4FDG chain B against the predicted model Q9UXG1: TM-score 0.89, RMSD 3.07 Å
- 6WNZ chain A against the predicted model Q9UXG1: TM-score 0.89, RMSD 2.32 Å
- 3F9V chain A against the predicted model Q9UXG1: TM-score 0.87, RMSD 3.23 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.