UniProt Q9UGL1
Lysine-specific demethylase 5B (Q9UGL1)
Lysine-specific demethylase 5B (UniProt Q9UGL1), EC 1.14.11.-: 96 experimental structures on GenesisL1, 43 ligands bound, 15 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- Q9UGL1
- Protein
- Lysine-specific demethylase 5B
- EC
- 1.14.11.-
- Experimental structures
- 96
- Predicted models
- 0
- Ligands
- 43
- Pockets
- 15 · 3 records with a druggable one
Structures
96 records of Q9UGL1 in the MolNFT archive: 96 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2MA5 | Solution NMR structure of PHD type Zinc finger domain of Lysine-specific demethylase 5B… | solution nmr | A | — | — |
| 2MA5 | Solution NMR structure of phd type zinc finger domain of lysine- specific demethylase 5B… | solution nmr | A | — | — |
| 2MNY | NMR Structure of KDM5B PHD1 finger | solution nmr | A | — | — |
| 2MNY | NMR structure of KDM5B PHD1 finger | solution nmr | A | — | — |
| 2MNZ | NMR Structure of KDM5B PHD1 finger in complex with H3K4me0(1-10aa) | solution nmr | A | — | — |
| 2MNZ | NMR structure of KDM5B PHD1 finger in complex with H3K4ME0(1-10AA) | solution nmr | A | — | — |
| 5A1F | Crystal structure of the catalytic domain of PLU1 in complex with N-oxalylglycine. | x-ray diffraction | A | ZN, OGA, MN, PO4 | 5 (best 0.75) |
| 5A1F | Crystal structure of the catalytic domain of PLU1 in complex with N-oxalylglycine. | x-ray diffraction | A | — | — |
| 5A3N | Crystal structure of human PLU-1 (JARID1B) in complex with KDOAM25a | x-ray diffraction | A | — | — |
| 5A3N | Crystal structure of human plu-1 (JARID1B) in complex with KDOAM25A | x-ray diffraction | A | — | — |
| 5A3P | Crystal structure of the catalytic domain of human PLU1 (JARID1B). | x-ray diffraction | A | — | — |
| 5A3P | Crystal structure of the catalytic domain of human PLU1 (JARID1B). | x-ray diffraction | A | — | — |
| 5A3T | Crystal structure of human PLU-1 (JARID1B) in complex with KDM5-C49… | x-ray diffraction | A | — | — |
| 5A3T | Crystal structure of human plu-1 (JARID1B) in complex with KDM5-C49… | x-ray diffraction | A | — | — |
| 5A3W | Crystal structure of human plu-1 (JARID1B) in complex with pyridine-2, 6-dicarboxylic acid (pdca) | x-ray diffraction | A | — | — |
| 5FPL | Crystal structure of human JARID1B in complex with CCT363901 | x-ray diffraction | A | ZN, MN, QAY | — |
| 5FPL | Crystal structure of human JARID1B in complex with CCT363901 | x-ray diffraction | A | — | — |
| 5FPU | Crystal structure of human JARID1B in complex with GSKJ1 | x-ray diffraction | A | ZN, K0I, MN, PO4 | — |
| 5FPU | Crystal structure of human JARID1B in complex with GSKJ1 | x-ray diffraction | A | — | — |
| 5FUN | Crystal structure of human JARID1B in complex with GSK467 | x-ray diffraction | A | ZN, GZA, MN, NA, PO4 | — |
| 5FUN | Crystal structure of human JARID1B in complex with GSK467 | x-ray diffraction | A | — | — |
| 5FUP | Crystal structure of human JARID1B in complex with 2-oxoglutarate. | x-ray diffraction | A | — | — |
| 5FV3 | Crystal structure of human JARID1B construct c2 in complex with N- Oxalylglycine. | x-ray diffraction | A | ZN, MN, CL, OGA | — |
| 5FV3 | Crystal structure of human JARID1B construct C2 in complex with N- oxalylglycine. | x-ray diffraction | A | — | — |
| 5FY4 | Crystal structure of the catalytic domain of human JARID1B in complex with succinate | x-ray diffraction | A | ZN, MN, FUM | — |
| 5FY4 | Crystal structure of the catalytic domain of human JARID1B in complex with succinate | x-ray diffraction | A | — | — |
| 5FY5 | Crystal structure of the catalytic domain of human JARID1B in complex with fumarate | x-ray diffraction | A | — | — |
| 5FY9 | Crystal structure of the catalytic domain of human JARID1B in complex with pyruvate | x-ray diffraction | A | MN, ZN, PYR | — |
| 5FY9 | Crystal structure of the catalytic domain of human JARID1B in complex with pyruvate | x-ray diffraction | A | — | — |
| 5FYB | Crystal structure of the catalytic domain of human JARID1B in complex with MC1648 | x-ray diffraction | A | — | — |
| 5FYS | Crystal structure of the catalytic domain of human JARID1B in complex with D-2-hydroxyglutarate | x-ray diffraction | A | — | — |
| 5FYS | Crystal structure of the catalytic domain of human JARID1B in complex with D-2-hydroxyglutarate | x-ray diffraction | A | — | — |
| 5FYT | Crystal structure of the catalytic domain of human JARID1B in complex with 3D fragment… | x-ray diffraction | A | ZN, MN, WQS, PO4, CL | — |
| 5FYT | Crystal structure of the catalytic domain of human JARID1B in complex with 3D fragment… | x-ray diffraction | A | — | — |
| 5FYU | Crystal structure of the catalytic domain of human JARID1B in complex with 3D fragment… | x-ray diffraction | A | ZN, MN, PO4, BY4, CL | — |
| 5FYU | Crystal structure of the catalytic domain of human JARID1B in complex with 3D fragment… | x-ray diffraction | A | — | — |
| 5FYV | Crystal structure of the catalytic domain of human JARID1B in complex with oxaloacetate | x-ray diffraction | A | ZN, MN, OAA, CL, PO4 | — |
| 5FYV | Crystal structure of the catalytic domain of human JARID1B in complex with oxaloacetate | x-ray diffraction | A | — | — |
| 5FYY | Crystal structure of the catalytic domain of human JARID1B in complex with Maybridge fragment… | x-ray diffraction | A | ZN, CL, MN, N6Y, PO4 | — |
| 5FYY | Crystal structure of the catalytic domain of human JARID1B in complex with maybridge fragment… | x-ray diffraction | A | — | — |
| 5FYZ | Crystal structure of the catalytic domain of human JARID1B in complex with 3D fragment… | x-ray diffraction | A | ZN, NYK, MN, PO4, NA | — |
| 5FYZ | Crystal structure of the catalytic domain of human JARID1B in complex with 3D fragment… | x-ray diffraction | A | — | — |
| 5FZ0 | Crystal structure of the catalytic domain of human JARID1B in complex with… | x-ray diffraction | A | ZN, MN, CL, DJ6, PO4 | — |
| 5FZ0 | Crystal structure of the catalytic domain of human JARID1B in complex with… | x-ray diffraction | A | — | — |
| 5FZ1 | Crystal structure of the catalytic domain of human JARID1B in complex with Maybridge fragment… | x-ray diffraction | A | ZN, MN, PO4, W77 | — |
| 5FZ1 | Crystal structure of the catalytic domain of human JARID1B in complex with maybridge fragment… | x-ray diffraction | A | — | — |
| 5FZ3 | Crystal structure of the catalytic domain of human JARID1B in complex with Maybridge fragment… | x-ray diffraction | A | ZN, MN, 7SI, CL, PO4 | — |
| 5FZ3 | Crystal structure of the catalytic domain of human JARID1B in complex with maybridge fragment… | x-ray diffraction | A | — | — |
| 5FZ4 | Crystal structure of the catalytic domain of human JARID1B in complex with 3D fragment… | x-ray diffraction | A | ZN, P6B, MN, CL, PO4 | — |
| 5FZ4 | Crystal structure of the catalytic domain of human JARID1B in complex with 3D fragment… | x-ray diffraction | A | — | — |
| 5FZ6 | Crystal structure of the catalytic domain of human JARID1B in complex with maybridge fragment… | x-ray diffraction | A | — | — |
| 5FZ7 | Crystal structure of the catalytic domain of human JARID1B in complex with Maybridge fragment ethyl… | x-ray diffraction | A | ZN, MN, PO4, CL, WGT | — |
| 5FZ7 | Crystal structure of the catalytic domain of human JARID1B in complex with maybridge fragment ethyl… | x-ray diffraction | A | — | — |
| 5FZ8 | Crystal structure of the catalytic domain of human JARID1B in complex with malate | x-ray diffraction | A | — | — |
| 5FZ9 | Crystal structure of the catalytic domain of human JARID1B in complex with maybridge fragment… | x-ray diffraction | A | — | — |
| 5FZA | Crystal structure of the catalytic domain of human JARID1B in complex with 3D fragment… | x-ray diffraction | A | — | — |
| 5FZB | Crystal structure of the catalytic domain of human JARID1B in complex with Maybridge fragment… | x-ray diffraction | A | ZN, MN, CL, YS6, PO4 | — |
| 5FZB | Crystal structure of the catalytic domain of human JARID1B in complex with maybridge fragment… | x-ray diffraction | A | — | — |
| 5FZC | Crystal structure of the catalytic domain of human JARID1B in complex with Maybridge fragment… | x-ray diffraction | A | ZN, MN, D8S, CL, PO4 | — |
| 5FZC | Crystal structure of the catalytic domain of human JARID1B in complex with maybridge fragment… | x-ray diffraction | A | — | — |
36 records more on the page itself.
Ligands
- MN · Manganese (II) ion · in 45 records
- ZN · Zinc ion · in 45 records
- PO4 · Phosphate ion · in 28 records
- CL · Chloride ion · in 17 records
- NA · Sodium ion · in 4 records
- 5UJ · 8-[4-[2-[4-[3,5-bis(chloranyl)phenyl]piperidin-1-yl]ethyl]pyrazol-1-yl]-3~{H}-pyrido[3,4-d]pyrimidin-4-one · in 2 records
- 79H · 5-[1-[2-(dimethylamino)ethyl]pyrazol-4-yl]-7-oxidanylidene-6-propan-2-yl-6~{H}-pyrazolo[1,5-a]pyrimidine-3-carbonitrile · in 2 records
- B7K · 7-oxidanylidene-6-propan-2-yl-5-[1-(1-prop-2-enoylpiperidin-4-yl)pyrazol-4-yl]-6~{H}-pyrazolo[1,5-a]pyrimidine-3-carbonitrile · in 2 records
- FO2 · 8-[4-(1-methylpiperidin-4-yl)pyrazol-1-yl]-3~{H}-pyrido[3,4-d]pyrimidin-4-one · in 2 records
- FQ5 · 8-[4-[2-[4-(3-chlorophenyl)piperidin-1-yl]ethyl]pyrazol-1-yl]-3~{H}-pyrido[3,4-d]pyrimidin-4-one · in 2 records
- FQK · 8-[4-[1-(cyclobutylmethyl)piperidin-4-yl]pyrazol-1-yl]-3~{H}-pyrido[3,4-d]pyrimidin-4-one · in 2 records
- JX8 · 5-(1~{H}-1,2,3,4-tetrazol-5-yl)quinolin-8-ol · in 2 records
- OGA · N-oxalylglycine · in 2 records
- 7IA · [(6-oxo-4-phenyl-1,6-dihydropyrimidin-2-yl)sulfanyl]acetic acid · in 1 record
- 7SI · (1R,4S)-1,2,3,4-tetrahydro-1,4-methanonaphthalene-5,8-diol · in 1 record
- 90V · N-{(3R)-1-[3-(propan-2-yl)-1H-pyrazole-5-carbonyl]pyrrolidin-3-yl}cyclopropanecarboxamide · in 1 record
- B6T · 8-oxidanyl-6-phenyl-7-propan-2-yl-imidazo[1,2-b]pyridazine-3-carbonitrile · in 1 record
- B6W · 2-chloranyl-~{N}-[2-[4-(3-cyano-7-oxidanylidene-6-propan-2-yl-4~{H}-pyrazolo[1,5-a]pyrimidin-5-yl) pyrazol-1-yl]ethyl]ethanamide · in 1 record
- B7Q · 5-[1-[1-(2-chloranylethanoyl)piperidin-4-yl]pyrazol-4-yl]-7-oxidanylidene-6-propan-2-yl-4~{H}-pyrazolo[1,5-a]pyrimidine-3-carbonitrile · in 1 record
- B7Z · 8-[4-[2-(4-propanoylpiperazin-1-yl)ethyl]pyrazol-1-yl]-3~{H}-pyrido[3,4-d]pyrimidin-4-one · in 1 record
- BY4 · (3R)-3-azanyl-4-methyl-1,3-dihydroindol-2-one · in 1 record
- D8S · benzo[g][1]benzothiole-2-carboxylic acid · in 1 record
- DJ6 · 2,5-dichloro-N-(pyridin-3-yl)thiophene-3-carboxamide · in 1 record
- FIG · 6-oxo-2-[(2-oxo-2-phenylethyl)sulfanyl]-1,6-dihydropyrimidine-5-carboxylic acid · in 1 record
- FQN · 8-[4-(1-cyclopentylpiperidin-4-yl)pyrazol-1-yl]-3~{H}-pyrido[3,4-d]pyrimidin-4-one · in 1 record
- FUM · Fumaric acid · in 1 record
- GZA · 2-[(1-benzyl-1H-pyrazol-4-yl)oxy]pyrido[3,4-d]pyrimidin-4(3H)-one · in 1 record
- H0X · [(6-oxo-4-phenyl-1,6-dihydropyrimidin-2-yl)sulfanyl]acetonitrile · in 1 record
- K0I · 3-[[2-pyridin-2-yl-6-(1,2,4,5-tetrahydro-3-benzazepin-3-yl)pyrimidin-4-yl]amino]propanoic acid · in 1 record
- N6Y · 3-(pyridin-3-yl)aniline · in 1 record
Elsewhere
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