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Ligand · MN1

MN1 · 4-carboxypiperidine

MN1, 4-carboxypiperidine (C6 H11 N O2, 129.2 g/mol), in the MolNFT structures on GenesisL1: bound in 4 records (4 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds most and the ligands found with it.

Component
MN1
Formula
C6 H11 N O2
Class
ligand
Structures
4
PDB entries
4

Binding sites

MN1 in 4 structures; the first of them:

  • 5FXV · Crystal structure of JmjC domain of human histone demethylase UTY in complex with N05859b · MN1 A2347 · binds PHE1031, TYR1082, LYS1084, THR1090, HIS1093, GLU1095, ASN1103, TRP1113 and 3 more
  • 5FZ6 · Crystal structure of the catalytic domain of human JARID1B in complex with Maybridge… · MN1 A1771 · binds TYR488, PHE496, HIS499, GLU501, ASN509, LYS517, TRP519, HIS587
  • 7M5U · Crystal structure of human MPP8 chromodomain in complex with peptidomimetic ligand UNC5246 · MN1 B1 · binds GLU60, VAL61, ASP98, GLU101, PHE2
  • 7N27 · Crystal structure of chromodomain of cdyl in complex with inhibitor UNC6261 · MN1 G1000 · binds GLU62, VAL63, VAL100, ASN101, CYS102, TYR105, PF51001, GLN97

Residues it binds most

VAL 9, ASN 9, GLU 10, TYR 9, GLN 6, HIS 3, PF5 6, CYS 4, PHE 4, LYS 3 (residue and the binding sites it lines).

Found with

  • MN · Manganese (II) ion
  • ZN · Zinc ion
  • EDO · 1,2-ethanediol
  • NA · Sodium ion
  • CL · Chloride ion
  • PO4 · Phosphate ion
  • UNX · Unknown atom or ion
  • DMS · Dimethyl sulfoxide
  • EPE · 4-(2-hydroxyethyl)-1-piperazine ethanesulfonic acid
  • MOH · Methanol

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