Ligand · FO2
FO2 · 8-[4-(1-methylpiperidin-4-yl)pyrazol-1-yl]-3~{H}-pyrido[3,4-d]pyrimidin-4-one
FO2, 8-[4-(1-methylpiperidin-4-yl)pyrazol-1-yl]-3~{H}-pyrido[3,4-d]pyrimidin-4-one (C16 H18 N6 O, 310.4 g/mol), in the MolNFT structures on GenesisL1: bound in 6 records (3 PDB entries). Every binding site with its residues within 4.5 Å…
- Component
- FO2
- Formula
- C16 H18 N6 O
- Class
- ligand
- Structures
- 6
- PDB entries
- 3
Binding sites
FO2 in 6 structures; the first of them:
- 6H4Q · Crystal structure of human KDM4A in complex with compound 34a · FO2 A403 · binds TYR132, TYR177, PHE185, HIS188, GLU190, ASP191, ASN198, LYS206 and 3 more
- 6H4U · Crystal structure of human KDM4A in complex with compound 34b · FO2 A403 · binds TYR132, ASP135, TYR177, PHE185, HIS188, GLU190, LYS206, TRP208 and 2 more
- 6H50 · Crystal structure of human KDM5B in complex with compound 34a · FO2 A809 · binds VAL99, TRP486, TYR488, PHE496, HIS499, GLU501, ASN509, LYS517 and 2 more
- 6H4Q · Crystal structure of human KDM4A in complex with compound 34A · FO2 A403 · binds TYR132, TYR177, PHE185, HIS188, GLU190, ASP191, ASN198, LYS206 and 3 more
- 6H4U · Crystal structure of human KDM4A in complex with compound 34B · FO2 A403 · binds TYR132, ASP135, TYR177, PHE185, HIS188, GLU190, LYS206, TRP208 and 2 more
- 6H50 · Crystal structure of human KDM5B in complex with compound 34A · FO2 A809 · binds VAL99, TRP486, TYR488, PHE496, HIS499, GLU501, ASN509, LYS517 and 2 more
Residues it binds most
TYR 18, HIS 18, LYS 18, GLU 18, TRP 18, PHE 18, ASP 14, ASN 12, GLY 10, VAL 6 (residue and the binding sites it lines).
Found with
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