UniProt Q969N2
GPI transamidase component PIG-T (Q969N2)
GPI transamidase component PIG-T (UniProt Q969N2): 6 experimental structures on GenesisL1, 8 ligands bound, 38 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- Q969N2
- Protein
- GPI transamidase component PIG-T
- Experimental structures
- 6
- Predicted models
- 0
- Ligands
- 8
- Pockets
- 38 · 3 records with a druggable one
Structures
6 records of Q969N2 in the MolNFT archive: 6 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7W72 | Structure of a human glycosylphosphatidylinositol (GPI) transamidase | electron microscopy | T | 8JY, NAG | 13 (best 0.87) |
| 7W72 | Structure of a human glycosylphosphatidylinositol (gpi) transamidase | electron microscopy | T | 8JY, NAG | — |
| 7WLD | Cryo-EM structure of the human glycosylphosphatidylinositol transamidase complex at 2.53 Angstrom… | electron microscopy | T | 05E, NAG, PA1, 06O | 11 (best 0.88) |
| 7WLD | Cryo-EM structure of the human glycosylphosphatidylinositol transamidase complex at 2.53 ångström… | electron microscopy | T | 05E, NAG, PA1, 06O | — |
| 8IMY | Cryo-EM structure of GPI-T (inactive mutant) with GPI and proULBP2, a proprotein substrate | electron microscopy | T | 6OU, 05E, LBN, NAG, 81Q, PA1 | 14 (best 0.86) |
| Q969N2 | AlphaFold monomer V2.0 prediction for gpi transamidase component pig-T (Q969N2) | — | — | — |
Ligands
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · in 5 records
- 05E · 2-azanylethyl [(2~{S},3~{S},4~{S},5~{S},6~{R})-6-(hydroxymethyl)-2,4,5-tris(oxidanyl)oxan-3-yl] hydrogen phosphate · in 3 records
- PA1 · 2-amino-2-deoxy-alpha-D-glucopyranose · in 3 records
- 06O · [(2~{R})-1-hexadecanoyloxy-3-[[(1~{S},2~{R},3~{R}, 4~{S},5~{S},6~{R})-2-hexadecanoyloxy-3,4,5,6-tetrakis(oxidanyl)cyclohexyl]oxy-oxidanyl-phosphoryl]oxy-propan-2-yl] (9~{Z},11~{Z})-octadeca-9, 11-dienoate · in 2 records
- 8JY · [2-[[(2~{R})-2-hexanoyloxy-3-[(~{E})-hex-3-enoxy]propoxy]-oxidanyl-phosphoryl]oxy-3,4,5,6-tetrakis(oxidanyl)phenyl] (2~{E},4~{E})-hepta-2,4-dienoate · in 2 records
- 6OU · [(2~{R})-1-[2-azanylethoxy(oxidanyl)phosphoryl]oxy-3-hexadecanoyloxy-propan-2-yl] (~{Z})-octadec-9-enoate · in 1 record
- 81Q · [(2R)-1-[[(1S,2R,3R,4S,5S,6R)-2-hexadecanoyloxy-3,4,5,6-tetrakis(oxidanyl)cyclohexyl]oxy-oxidanyl-phosphoryl]oxy-3-octadecoxy-propan-2-yl] (5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoate · in 1 record
- LBN · 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine · in 1 record
Experiment against prediction
- 8IMY chain T against the predicted model Q9U6Y3: TM-score 0.18, RMSD 6.78 Å
Elsewhere
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