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Ligand · 6OU

6OU · [(2~{R})-1-[2-azanylethoxy(oxidanyl)phosphoryl]oxy-3-hexadecanoyloxy-propan-2-yl] (~{Z})-octadec-9-enoate

6OU, [(2~{R})-1-[2-azanylethoxy(oxidanyl)phosphoryl]oxy-3-hexadecanoyloxy-propan-2-yl] (~{Z})-octadec-9-enoate (C39 H76 N O8 P, 718.0 g/mol), in the MolNFT structures on GenesisL1: bound in 85 records (60 PDB entries). Every binding site…

Component
6OU
Formula
C39 H76 N O8 P
Class
ligand
Structures
85
PDB entries
60

Binding sites

6OU in 85 structures; the first of them:

  • 5H5A · Mdm12 from K. lactis (1-239), Lys residues are uniformly dimethyl modified · 6OU A301 · binds ILE5, ILE10, VAL16, VAL20, LEU24, PHE45, LEU47, PRO52 and 21 more
  • 5JXD · Crystal structure of murine Tnfaip8 C165S mutant · 6OU A201 · binds THR40, THR41, SER47, VAL50, LEU51, LEU54, LEU75, VAL79 and 23 more
  • 6BR8 · Structure of A6 reveals a novel lipid transporter · 6OU A401 · binds ILE223, LEU266, VAL270, GLU273, ILE274, LEU280, VAL341, ILE344 and 10 more
  • 6N4I · Structural basis of Nav1.7 inhibition by a gating-modifier spider toxin · 6OU A1001 · binds ILE858, MET861, THR862, PHE865, LEU887, GLY888, GLU889, PHE891 and 5 more
  • 6PQO · Cryo-EM structure of the human TRPA1 ion channel in complex with the covalent agonist… · 6OU D1306 · binds TYR926, VAL935, PHE938, ALA939, VAL942, ILE946, PHE947, SER900 and 3 more

Residues it binds most

LEU 570, ILE 505, PHE 506, TYR 427, VAL 340, ALA 240, SER 225, MET 166, THR 187, LYS 169 (residue and the binding sites it lines).

Found with

  • LBN · 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine
  • NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose
  • NA · Sodium ion
  • BMA · beta-D-mannopyranose
  • 9Z9 · (3beta,14beta,17beta,25R)-3-[4-methoxy-3-(methoxymethyl)butoxy]spirost-5-en
  • 6EU · resiniferatoxin
  • YFP · 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphoglycerol
  • 4DY · (6E)-N-(4-hydroxy-3-methoxybenzyl)-8-methylnon-6-enamide
  • CA · Calcium ion
  • OLA · Oleic acid
  • T7X · Phosphatidylinositol
  • PGV · (1R)-2-{[{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy) phosphoryl]oxy}-1-[(palmitoyloxy)methyl]ethyl (11E)-octadec-11-enoate

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