4DY · (6E)-N-(4-hydroxy-3-methoxybenzyl)-8-methylnon-6-enamide

Binding sites

4DY in 7 structures; the first of them:

• 7LPA · Cryo-EM structure of full-length TRPV1 with capsaicin at 4 degrees Celsius · 4DY A905 · binds TYR511, SER512, LEU515, PHE543, THR550, ASN551, TYR554, ARG557 and 4 more
• 7LPA · Cryo-EM structure of full-length TRPV1 with capsaicin at 4 degrees celsius · 4DY A905 · binds TYR511, SER512, LEU515, PHE543, THR550, ASN551, TYR554, ARG557 and 4 more
• 7LPB · Cryo-EM structure of full-length TRPV1 with capsaicin at 25 degrees celsius · 4DY A3000 · binds TYR511, SER512, LEU515, PHE543, ALA546, THR550, ASN551, TYR554 and 3 more
• 7LPD · Cryo-EM structure of full-length TRPV1 with capsaicin at 48 degrees celsius, in an… · 4DY A904 · binds TYR511, SER512, LEU515, PHE543, ALA546, THR550, ASN551, LEU553 and 6 more
• 7LPE · Cryo-EM structure of full-length TRPV1 with capsaicin at 48 degrees celsius, in an open… · 4DY C1003 · binds TYR511, SER512, LEU515, PHE543, MET547, THR550, ASN551, TYR554 and 8 more
• 7LR0 · Structure of squirrel TRPV1 in complex with capsaicin · 4DY A903 · binds TYR513, SER514, LEU517, PHE518, PHE545, THR552, ASN553, LEU555 and 5 more
• 7VEK · Crystal structure of phytolacca americana UGT3 with capsaicin and udp- 2FLUOROGLUCOSE · 4DY B501 · binds HIS20, MET125, PHE126, HIS145, THR147, LEU155, VAL158, ARG159 and 8 more

Residues it binds most

LEU 25, TYR 25, PHE 25, THR 25, ASN 24, ILE 24, SER 24, ALA 13, ARG 17, GLU 13 (residue and the binding sites it lines).

Found with

• 6OU · [(2~{R})-1-[2-azanylethoxy(oxidanyl)phosphoryl]oxy-3-hexadecanoyloxy-propan-2-yl] (~{Z})-octadec-9-enoate
• LBN · 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine
• YFP · 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphoglycerol
• NA · Sodium ion
• O4B · 1,4,7,10,13,16-hexaoxacyclooctadecane
• POV · (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate
• U2F · Uridine-5'-diphosphate-2-deoxy-2-fluoro-alpha-D-glucose
• K · Potassium ion