UniProt Q94BU8
Guanosine deaminase (Q94BU8)
Guanosine deaminase (UniProt Q94BU8), EC 3.5.4.15: 31 experimental structures and 1 predicted model on GenesisL1, 13 ligands bound, 44 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q94BU8
- Protein
- Guanosine deaminase
- EC
- 3.5.4.15
- Experimental structures
- 31
- Predicted models
- 1
- Ligands
- 13
- Pockets
- 44 · 16 records with a druggable one
Structures
32 records of Q94BU8 in the MolNFT archive: 31 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7DBF | The structure of the Arabidopsis thaliana guanosine deaminase | x-ray diffraction | A, D | ZN | 3 (best 0.67) |
| 7DBF | The structure of the arabidopsis thaliana guanosine deaminase | x-ray diffraction | A, D | ZN | — |
| 7DC9 | The structure of the Arabidopsis thaliana guanosine deaminase mutant E82Q complex with guanosine | x-ray diffraction | A, D | ZN, GMP | 2 (best 0.80) |
| 7DC9 | The structure of the arabidopsis thaliana guanosine deaminase mutant E82Q complex with guanosine | x-ray diffraction | A, D | ZN, GMP | — |
| 7DCA | The structure of the Arabidopsis thaliana guanosine deaminase bound by xanthosine | x-ray diffraction | A, D | 4UO, ZN | 3 (best 0.78) |
| 7DCA | The structure of the arabidopsis thaliana guanosine deaminase bound by xanthosine | x-ray diffraction | A, D | 4UO, ZN | — |
| 7DCB | The structure of the Arabidopsis thaliana guanosine deaminase complexed with inosine | x-ray diffraction | A, D | ZN, NOS | 3 (best 0.78) |
| 7DCB | The structure of the arabidopsis thaliana guanosine deaminase complexed with inosine | x-ray diffraction | A, D | ZN, NOS | — |
| 7DCW | The structure of the Arabidopsis thaliana guanosine deaminase complexed with adenosine | x-ray diffraction | A, D | ZN, ADN | 3 (best 0.76) |
| 7DCW | The structure of the arabidopsis thaliana guanosine deaminase complexed with adenosine | x-ray diffraction | A, D | ZN, ADN | — |
| 7DGC | The structure of the Arabidopsis thaliana guanosine deaminase in reaction with 2'-O-Methylguanosine | x-ray diffraction | A, D | H5C, ZN, NA | 3 (best 0.78) |
| 7DGC | The structure of the arabidopsis thaliana guanosine deaminase in reaction with 2'-O-methylguanosine | x-ray diffraction | A, D | H5C, ZN, NA | — |
| 7DH1 | The structure of the Arabidopsis thaliana guanosine deaminase in reaction with N2-Methylguanosine | x-ray diffraction | A, D | ZN, 4UO | 3 (best 0.79) |
| 7DH1 | The structure of the arabidopsis thaliana guanosine deaminase in reaction with N2-methylguanosine | x-ray diffraction | A, D | ZN, 4UO | — |
| 7DLC | The structure of the Arabidopsis thaliana guanosine deaminase in reaction with N1-methylguanosine | x-ray diffraction | A, D | ZN, H93 | 3 (best 0.77) |
| 7DLC | The structure of the arabidopsis thaliana guanosine deaminase in reaction with N1-methylguanosine | x-ray diffraction | A, D | ZN, H93 | — |
| 7DM5 | The structure of the Arabidopsis thaliana guanosine deaminase in reaction with guanosine | x-ray diffraction | A, D | ZN, 4UO | 2 (best 0.78) |
| 7DM5 | The structure of the arabidopsis thaliana guanosine deaminase in reaction with guanosine | x-ray diffraction | A, D | ZN, 4UO | — |
| 7DM6 | The structure of the Arabidopsis thaliana guanosine deaminase complexed with crotonoside | x-ray diffraction | A, D | ZN, H5F | 3 (best 0.79) |
| 7DM6 | The structure of the arabidopsis thaliana guanosine deaminase complexed with crotonoside | x-ray diffraction | A, D | ZN, H5F | — |
| 7DOW | The structure of the Arabidopsis thaliana guanosine deaminase in reaction with 7-deazaguansoine | x-ray diffraction | A, D | HD3, ZN | 3 (best 0.79) |
| 7DOW | The structure of the arabidopsis thaliana guanosine deaminase in reaction with 7-deazaguansoine | x-ray diffraction | A, D | HD3, ZN | — |
| 7DOX | The structure of the Arabidopsis thaliana guanosine deaminase in complex with m7G | x-ray diffraction | A, D | ZN, MG7 | 2 (best 0.78) |
| 7DOX | The structure of the arabidopsis thaliana guanosine deaminase in complex with M7G | x-ray diffraction | A, D | ZN, MG7 | — |
| 7DOY | The structure of the Arabidopsis thaliana guanosine deaminase in complex with 6-O-methylguanosine | x-ray diffraction | A, D | HD9, ZN | 3 (best 0.79) |
| 7DOY | The structure of the arabidopsis thaliana guanosine deaminase in complex with 6-O-methylguanosine | x-ray diffraction | A, D | HD9, ZN | — |
| 7DPK | The structure of the exchange reaction of the Arabidopsis thaliana guanosine deaminase in complex… | x-ray diffraction | A, D | 4UO, ZN | 2 (best 0.76) |
| 7DPK | The structure of the exchange reaction of the arabidopsis thaliana guanosine deaminase in complex… | x-ray diffraction | A, D | 4UO, ZN | — |
| 7DQN | The structure of the Arabidopsis thaliana guanosine deaminase mutant Y185F complexed with guanosine | x-ray diffraction | A, D | GMP, ZN | 3 (best 0.77) |
| 7DQN | The structure of the arabidopsis thaliana guanosine deaminase mutant Y185F complexed with guanosine | x-ray diffraction | A, D | GMP, ZN | — |
| 7W1Q | The structure of the Arabidopsis thaliana guanosine deaminase mutant E82Q complexed with… | x-ray diffraction | A, D | ZN, OMG | 3 (best 0.78) |
| Q94BU8 | AlphaFold monomer V2.0 prediction for guanosine deaminase (Q94BU8) | predicted | A | — | — |
Ligands
- ZN · Zinc ion · in 31 records
- 4UO · 2,3-dihydroxanthosine · in 8 records
- GMP · Guanosine · in 4 records
- ADN · Adenosine · in 2 records
- H5C · 9-[(2R,3R,4R)-5-(hydroxymethyl)-3-methoxy-4-oxidanyl-oxolan-2-yl]-3H-purine-2,6-dione · in 2 records
- H5F · 6-azanyl-9-[(2R,3R,4S,5R)-5-(hydroxymethyl)-3,4-bis(oxidanyl)oxolan-2-yl]-1H-purin-2-one · in 2 records
- H93 · 2-azanyl-9-[(2R,3R,4S,5R)-5-(hydroxymethyl)-3,4-bis(oxidanyl)oxolan-2-yl]-1-methyl-purin-6-one · in 2 records
- HD3 · 2-azanyl-7-[(2R,3R,4S,5R)-5-(hydroxymethyl)-3,4-bis(oxidanyl)oxolan-2-yl]-3H-pyrrolo[2,3-d]pyrimidin-4-one · in 2 records
- HD9 · (2R,3R,4S,5R)-2-(2-azanyl-6-methoxy-purin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol · in 2 records
- MG7 · 7-methylguanosine · in 2 records
- NA · Sodium ion · in 2 records
- NOS · Inosine · in 2 records
- OMG · O2'-methylguanosine-5'-monophosphate · in 1 record
Experiment against prediction
- 7DLC chain D against the predicted model Q94BU8: TM-score 0.95, RMSD 1.52 Å
- 7DLC chain D against the predicted model Q94BU8: TM-score 0.95, RMSD 1.52 Å
- 7DBF chain A against the predicted model Q94BU8: TM-score 0.95, RMSD 1.48 Å
- 7DBF chain A against the predicted model Q94BU8: TM-score 0.95, RMSD 1.48 Å
- 7W1Q chain A against the predicted model Q94BU8: TM-score 0.95, RMSD 1.50 Å
- 7DPK chain A against the predicted model Q94BU8: TM-score 0.95, RMSD 1.50 Å
- 7DPK chain A against the predicted model Q94BU8: TM-score 0.95, RMSD 1.50 Å
- 7DOX chain D against the predicted model Q94BU8: TM-score 0.95, RMSD 1.55 Å
- 7DOX chain D against the predicted model Q94BU8: TM-score 0.95, RMSD 1.55 Å
- 7DC9 chain D against the predicted model Q94BU8: TM-score 0.95, RMSD 1.56 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.