UniProt Q4G1L2
Toll-like receptor 5b, Variable lymphocyte receptor B chimera (Q4G1L2)
Toll-like receptor 5b, Variable lymphocyte receptor B chimera (UniProt Q4G1L2), EC 3.2.2.6: 62 experimental structures on GenesisL1, 6 ligands bound, 28 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- Q4G1L2
- Protein
- Toll-like receptor 5b, Variable lymphocyte receptor B chimera
- EC
- 3.2.2.6
- Experimental structures
- 62
- Predicted models
- 0
- Ligands
- 6
- Pockets
- 28 · 4 records with a druggable one
Structures
62 records of Q4G1L2 in the MolNFT archive: 62 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2O6R | Structural diversity of the hagfish Variable Lymphocyte Receptors B61 | x-ray diffraction | A | — | — |
| 2O6R | Structural diversity of the hagfish variable lymphocyte receptors B61 | x-ray diffraction | A | — | — |
| 2Z62 | Crystal structure of the TV3 hybrid of human TLR4 and hagfish VLRB.61 | x-ray diffraction | A | — | — |
| 2Z62 | Crystal structure of the TV3 hybrid of human TLR4 and hagfish VLRB.61 | x-ray diffraction | A | — | — |
| 2Z63 | Crystal structure of the TV8 hybrid of human TLR4 and hagfish VLRB.61 | x-ray diffraction | A | — | — |
| 2Z63 | Crystal structure of the TV8 hybrid of human TLR4 and hagfish VLRB.61 | x-ray diffraction | A | — | — |
| 2Z65 | Crystal structure of the human TLR4 TV3 hybrid-MD-2-Eritoran complex | x-ray diffraction | A, B | — | — |
| 2Z65 | Crystal structure of the human TLR4 TV3 hybrid-md-2-eritoran complex | x-ray diffraction | A, B | — | — |
| 2Z66 | Crystal structure of the VT3 hybrid of human TLR4 and hagfish VLRB.61 | x-ray diffraction | A, B, C, D | — | — |
| 2Z66 | Crystal structure of the VT3 hybrid of human TLR4 and hagfish VLRB.61 | x-ray diffraction | A, B, C, D | — | — |
| 2Z7X | Crystal structure of the TLR1-TLR2 heterodimer induced by binding of a tri-acylated lipopeptide | x-ray diffraction | A, B | — | — |
| 2Z7X | Crystal structure of the TLR1-TLR2 heterodimer induced by binding of a tri-acylated lipopeptide | x-ray diffraction | A, B | — | — |
| 2Z80 | Crystal structure of the TLR1-TLR2 heterodimer induced by binding of a tri-acylated lipopeptide | x-ray diffraction | A, B | — | — |
| 2Z80 | Crystal structure of the TLR1-TLR2 heterodimer induced by binding of a tri-acylated lipopeptide | x-ray diffraction | A, B | — | — |
| 2Z81 | Crystal structure of the TLR1-TLR2 heterodimer induced by binding of a tri-acylated lipopeptide | x-ray diffraction | A | — | — |
| 2Z81 | Crystal structure of the TLR1-TLR2 heterodimer induced by binding of a tri-acylated lipopeptide | x-ray diffraction | A | — | — |
| 2Z82 | Crystal structure of the TLR1-TLR2 heterodimer induced by binding of a tri-acylated lipopeptide | x-ray diffraction | A | — | — |
| 2Z82 | Crystal structure of the TLR1-TLR2 heterodimer induced by binding of a tri-acylated lipopeptide | x-ray diffraction | A | — | — |
| 3A79 | Crystal structure of TLR2-TLR6-Pam2CSK4 complex | x-ray diffraction | A | — | — |
| 3A79 | Crystal structure of TLR2-TLR6-PAM2CSK4 complex | x-ray diffraction | A | — | — |
| 3A7B | Crystal structure of TLR2-Streptococcus Pneumoniae lipoteichoic acid complex | x-ray diffraction | A | — | — |
| 3A7B | Crystal structure of TLR2-streptococcus pneumoniae lipoteichoic acid complex | x-ray diffraction | A | — | — |
| 3A7C | Crystal structure of TLR2-PE-DTPA complex | x-ray diffraction | A | — | — |
| 3A7C | Crystal structure of TLR2-pe-dtpa complex | x-ray diffraction | A | — | — |
| 3UL7 | Crystal structure of the TV3 mutant F63W | x-ray diffraction | A | — | — |
| 3UL7 | Crystal structure of the TV3 mutant F63W | x-ray diffraction | A | — | — |
| 3UL8 | Crystal structure of the TV3 mutant V134L | x-ray diffraction | A | — | — |
| 3UL8 | Crystal structure of the TV3 mutant V134L | x-ray diffraction | A | — | — |
| 3UL9 | structure of the TV3 mutant M41E | x-ray diffraction | A | — | — |
| 3UL9 | Structure of the TV3 mutant M41E | x-ray diffraction | A | — | — |
| 3ULA | Crystal structure of the TV3 mutant F63W-MD-2-Eritoran complex | x-ray diffraction | A, C | — | — |
| 3ULA | Crystal structure of the TV3 mutant F63W-md-2-eritoran complex | x-ray diffraction | A, C | — | — |
| 3V44 | Crystal structure of the N-terminal fragment of zebrafish TLR5 | x-ray diffraction | A | — | — |
| 3V44 | Crystal structure of the N-terminal fragment of zebrafish TLR5 | x-ray diffraction | A | — | — |
| 3V47 | Crystal structure of the N-terminal fragment of zebrafish TLR5 in complex with Salmonella flagellin | x-ray diffraction | A, B | — | — |
| 3V47 | Crystal structure of the N-terminal fragment of zebrafish TLR5 in complex with salmonella flagellin | x-ray diffraction | A, B | — | — |
| 4ARN | Crystal structure of the N-terminal domain of Drosophila Toll receptor | x-ray diffraction | A, B, C, D | — | — |
| 4ARN | Crystal structure of the N-terminal domain of drosophila toll receptor | x-ray diffraction | A, B, C, D | — | — |
| 4ARR | Crystal structure of the N-terminal domain of Drosophila Toll receptor with the magic triangle I3C | x-ray diffraction | A, B | — | — |
| 4ARR | Crystal structure of the N-terminal domain of drosophila toll receptor with the magic triangle I3C | x-ray diffraction | A, B | — | — |
| 4BV4 | Structure and allostery in Toll-Spatzle recognition | x-ray diffraction | R | — | — |
| 4BV4 | Structure and allostery in toll-spatzle recognition | x-ray diffraction | R | — | — |
| 4QDH | Crystal Structure of the C-terminal Domain of Mouse TLR9 | x-ray diffraction | A, B | — | — |
| 4QDH | Crystal structure of the C-terminal domain of mouse TLR9 | x-ray diffraction | A, B | — | — |
| 4QXE | Crystal structure of LGR4 fused with hagfish VLR | x-ray diffraction | A | — | — |
| 4QXE | Crystal structure of LGR4 fused with hagfish vlr | x-ray diffraction | A | — | — |
| 4QXF | crystal structure of human LGR4 and Rspo1 | x-ray diffraction | A, B | — | — |
| 4QXF | Crystal structure of human LGR4 and RSPO1 | x-ray diffraction | A, B | — | — |
| 5GY2 | Crystal structure of a complex between Bacillus subtilis flagellin and zebrafish Toll-like receptor… | x-ray diffraction | A, B | NAG | — |
| 5GY2 | Crystal structure of a complex between bacillus subtilis flagellin and zebrafish toll-like receptor… | x-ray diffraction | A, B | — | — |
| 5IJB | The ligand-free structure of the mouse TLR4/MD-2 complex | x-ray diffraction | A, B | NAG | — |
| 5IJB | The ligand-free structure of the mouse TLR4/MD-2 complex | x-ray diffraction | A, B | — | — |
| 5IJC | The crystal structure of mouse TLR4/MD-2/neoseptin-3 complex | x-ray diffraction | A, B | NAG, V2A | — |
| 5IJC | The crystal structure of mouse TLR4/MD-2/NEOSEPTIN-3 complex | x-ray diffraction | A, B | — | — |
| 5IJD | The crystal structure of mouse TLR4/MD-2/lipid A complex | x-ray diffraction | A, B | NAG, LP4, LP5, MYR | 8 (best 0.80) |
| 5IJD | The crystal structure of mouse TLR4/MD-2/LIPID a complex | x-ray diffraction | A, B | — | — |
| 6BXA | Crystal structure of N-terminal fragment of Zebrafish Toll-Like Receptor 5 (TLR5) with Lamprey… | x-ray diffraction | A, B | NAG | 6 (best 0.73) |
| 6BXA | Crystal structure of N-terminal fragment of zebrafish toll-like receptor 5 (TLR5) with lamprey… | x-ray diffraction | A, B | NAG | — |
| 6BXC | Crystal structure of N-terminal fragment of Zebrafish Toll-Like Receptor 5 (TLR5) with Lamprey… | x-ray diffraction | A, B | NAG | 12 (best 0.74) |
| 6BXC | Crystal structure of N-terminal fragment of zebrafish toll-like receptor 5 (TLR5) with lamprey… | x-ray diffraction | A, B | NAG | — |
2 records more on the page itself.
Ligands
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · in 10 records
- ZKM · N-[(1S,2R,3E)-2-hydroxy-1-{[(3-O-sulfo-beta-D-galactopyranosyl)oxy]methyl}heptadec-3-en-1-yl]-hexadecanamide · in 2 records
- LP4 · 2-deoxy-3-O-[(3R)-3-hydroxytetradecanoyl]-2-{[(3R)-3-hydroxytetradecanoyl]amino}-4-O-phosphono-beta-D-glucopyranose · in 1 record
- LP5 · (R)-((2R,3S,4R,5R,6R)-3-hydroxy-2-(hydroxymethyl)-5-((R)-3-hydroxytetradecanamido)-6-(phosphonooxy) tetrahydro-2H-pyran-4-yl) 3-hydroxytetradecanoate · in 1 record
- MYR · Myristic acid · in 1 record
- V2A · neoseptin 3 · in 1 record
Experiment against prediction
- 7MLM chain A against the predicted model Q9QUK6: TM-score 0.99, RMSD 0.94 Å
- 7MLM chain A against the predicted model Q9QUK6: TM-score 0.99, RMSD 0.94 Å
- 5IJC chain A against the predicted model Q9QUK6: TM-score 0.99, RMSD 0.95 Å
- 5IJC chain A against the predicted model Q9QUK6: TM-score 0.99, RMSD 0.95 Å
- 5IJD chain A against the predicted model Q9QUK6: TM-score 0.99, RMSD 1.00 Å
- 5IJD chain A against the predicted model Q9QUK6: TM-score 0.99, RMSD 1.00 Å
- 5IJD chain B against the predicted model Q9QUK6: TM-score 0.99, RMSD 1.02 Å
- 5IJD chain B against the predicted model Q9QUK6: TM-score 0.99, RMSD 1.02 Å
- 5IJC chain B against the predicted model Q9QUK6: TM-score 0.98, RMSD 1.04 Å
- 5IJC chain B against the predicted model Q9QUK6: TM-score 0.98, RMSD 1.04 Å
Elsewhere
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