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Ligand · LTC

LTC · (2S)-1-({3-O-[2-(acetylamino)-4-amino-2,4,6-trideoxy-beta-D-galactopyranosyl]-alpha-D-glucopyranosyl}oxy)-3-(heptanoyloxy)propan-2-yl (7Z)-pentadec-7-enoate

LTC, (2S)-1-({3-O-[2-(acetylamino)-4-amino-2,4,6-trideoxy-beta-D-galactopyranosyl]-alpha-D-glucopyranosyl}oxy)-3-(heptanoyloxy)propan-2-yl (7Z)-pentadec-7-enoate (C39 H70 N2 O13, 775.0 g/mol), in the MolNFT structures on GenesisL1: bound…

Component
LTC
Formula
C39 H70 N2 O13
Class
ligand
Structures
6
PDB entries
3

Binding sites

LTC in 6 structures; the first of them:

  • 3A7B · Crystal structure of TLR2-Streptococcus Pneumoniae lipoteichoic acid complex · LTC A581 · binds PHE266, LEU306, VAL312, ILE314, LEU317, ILE319, PRO320, GLN321 and 13 more
  • 3O4K · Crystal structure of the complex of peptidoglycan recognition protein (PGRP-S) and… · LTC C172 · binds ARG31, TYR32, SER139, ASN140, GLU142, LYS144, ARG170, ALA171 and 26 more
  • 3SDF · Crystal Structure of C-lobe of Bovine lactoferrin Complexed with Lipoteichoic acid at 2.1… · LTC A172 · binds LYS419, HIS420, PRO429, THR430, GLU431, GLY432, VAL591, ALA592 and 7 more
  • 3A7B · Crystal structure of TLR2-streptococcus pneumoniae lipoteichoic acid complex · LTC A581 · binds PHE266, LEU306, VAL312, ILE314, LEU317, ILE319, PRO320, GLN321 and 13 more
  • 3O4K · Crystal structure of the complex of peptidoglycan recognition protein (pgrp-S) and… · LTC C172 · binds ARG31, TYR32, SER139, ASN140, GLU142, LYS144, ARG170, ALA171 and 26 more
  • 3SDF · Crystal structure of C-lobe of bovine lactoferrin complexed with lipoteichoic acid at 2.1… · LTC A172 · binds LYS419, HIS420, PRO429, THR430, GLU431, GLY432, VAL591, ALA592 and 7 more

Residues it binds most

LEU 6, PRO 6, ALA 4, GLU 4, GLY 4, LYS 6, VAL 6, PHE 2, ASN 2, GLN 4 (residue and the binding sites it lines).

Found with

  • NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose
  • FE · Fe (III) ion
  • ZN · Zinc ion
  • BMA · beta-D-mannopyranose
  • CO3 · Carbonate ion
  • SO4 · Sulfate ion
  • GOL · Glycerol
  • TLA · L(+)-tartaric acid

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