UniProt Q15907
RAB11B, member RAS oncogene family (Q15907)
RAB11B, member RAS oncogene family (UniProt Q15907), EC 3.6.5.2: 6 experimental structures and 1 predicted model on GenesisL1, 4 ligands bound, 9 pockets. Binding sites, druggability and experiment against prediction (TM-score)…
- UniProt
- Q15907
- Protein
- RAB11B, member RAS oncogene family
- EC
- 3.6.5.2
- Experimental structures
- 6
- Predicted models
- 1
- Ligands
- 4
- Pockets
- 9 · 1 record with a druggable one
Structures
7 records of Q15907 in the MolNFT archive: 6 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2F9L | 3D structure of inactive human Rab11b GTPase | x-ray diffraction | A | MG, GDP | 1 (best 0.32) |
| 2F9L | 3D structure of inactive human RAB11B GTPase | x-ray diffraction | A | MG, GDP | 1 (best 0.32) |
| 2F9M | 3D structure of active human Rab11b GTPase | x-ray diffraction | A | MG, NI, GNP | 1 (best 0.44) |
| 2F9M | 3D structure of active human RAB11B GTPase | x-ray diffraction | A | MG, NI, GNP | 1 (best 0.44) |
| 4OJK | Structure of the cGMP Dependent Protein Kinase II and Rab11b Complex | x-ray diffraction | A, B | GDP | 4 (best 0.65) |
| 4OJK | Structure of the cgmp dependent protein kinase II and RAB11B complex | x-ray diffraction | A, B | — | — |
| Q15907 | AlphaFold monomer V2.0 prediction for RAS-related protein rab-11B (Q15907) | predicted | A | — | 1 (best 0.44) |
Ligands
Experiment against prediction
- 4OJK chain B against the predicted model Q15907: TM-score 0.98, RMSD 0.74 Å
- 4OJK chain B against the predicted model Q15907: TM-score 0.98, RMSD 0.74 Å
- 2F9M chain A against the predicted model Q15907: TM-score 0.97, RMSD 1.02 Å
- 2F9M chain A against the predicted model Q15907: TM-score 0.97, RMSD 1.02 Å
- 2F9L chain A against the predicted model Q15907: TM-score 0.95, RMSD 1.41 Å
- 2F9L chain A against the predicted model Q15907: TM-score 0.95, RMSD 1.41 Å
- 4OJK chain A against the predicted model Q15907: TM-score 0.95, RMSD 1.48 Å
- 4OJK chain A against the predicted model Q15907: TM-score 0.95, RMSD 1.48 Å
Elsewhere
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