MolNFT v1 · #36567 · protein

3D structure of inactive human RAB11B GTPase

2F9L · RAB11B, member RAS oncogene family: “3D structure of inactive human RAB11B GTPase”. X-ray diffraction, 2 ligands (GDP, MG), 1 pocket (best druggability 0.32). MolNFT v1 #36567 on GenesisL1: 3D structure, binding sites and pockets in…

PDB: 2F9L
Type: protein
Length: 173 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: RAB11B, member RAS oncogene family
EC: 3.6.5.2
UniProt: Q15907
Ligands: GDP, MG
Pockets: 1 · best druggability 0.32

Structure

x-ray diffraction · 1 distinct chain · 36% helix, 25% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	RAB11B, member RAS oncogene family (EC 3.6.5.2)	protein	173	36% helix, 25% strand	Q15907

Ligands and binding sites

GDP · Guanosine-5'-diphosphate · ligand · chains A
MG · Magnesium ion · metal · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	78	0.32	0.75	25	MG, GDP

Compared structures

2F9L · 3D structure of inactive human Rab11b GTPase · the same entry in another collection · chain A against A, TM-score 1.00
Q15907 · AlphaFold monomer V2.0 prediction for RAS-related protein rab-11B (Q15907) · a predicted model of the same protein · chain A against A, TM-score 0.95

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q15907
Elsewhere: RCSB PDB 2F9L · PDBe 2F9L · UniProt Q15907

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