MolNFT v1 · #36568 · protein
3D structure of active human RAB11B GTPase
2F9M · RAB11B, member RAS oncogene family: “3D structure of active human RAB11B GTPase”. X-ray diffraction, 3 ligands (GNP, NI, MG), 1 pocket (best druggability 0.44). MolNFT v1 #36568 on GenesisL1: 3D structure, binding sites and pockets…
- PDB
- 2F9M
- Type
- protein
- Length
- 182 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- RAB11B, member RAS oncogene family
- EC
- 3.6.5.2
- UniProt
- Q15907
- Ligands
- GNP, NI, MG
- Pockets
- 1 · best druggability 0.44
Structure
x-ray diffraction · 1 distinct chain · 40% helix, 25% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | RAB11B, member RAS oncogene family (EC 3.6.5.2) | protein | 182 | 40% helix, 25% strand | Q15907 |
Ligands and binding sites
- GNP · Phosphoaminophosphonic acid-guanylate ester · ligand · chains A
- NI · Nickel (II) ion · metal · 2 copies · chains A
- MG · Magnesium ion · metal · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 102 | 0.44 | 0.79 | 26 | MG, GNP |
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q15907
- Elsewhere: RCSB PDB 2F9M · PDBe 2F9M · UniProt Q15907
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