UniProt Q14974
Importin subunit beta-1 (Q14974)
Importin subunit beta-1 (UniProt Q14974): 28 experimental structures and 1 predicted model on GenesisL1, 22 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q14974
- Protein
- Importin subunit beta-1
- Experimental structures
- 28
- Predicted models
- 1
- Pockets
- 22 · 2 records with a druggable one
Structures
29 records of Q14974 in the MolNFT archive: 28 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1F59 | Importin-beta-fxfg nucleoporin complex | x-ray diffraction | A, B | — | — |
| 1F59 | Importin-beta-fxfg nucleoporin complex | x-ray diffraction | A, B | — | — |
| 1IBR | Complex of ran with importin beta | x-ray diffraction | B, D | — | — |
| 1IBR | Complex of ran with importin beta | x-ray diffraction | B, D | — | — |
| 1M5N | Crystal structure of HEAT repeats (1-11) of importin b bound to the non-classical NLS(67-94) of… | x-ray diffraction | S | — | — |
| 1M5N | Crystal structure of heat repeats (1-11) of importin B bound to the non-classical NLS(67-94) of… | x-ray diffraction | S | — | — |
| 1O6O | Importin Beta aa1-442 bound to five FxFG repeats from yeast Nsp1p. Second crystal form | x-ray diffraction | A, B, C | — | — |
| 1O6O | Importin beta AA1-442 bound to five fxfg repeats from yeast NSP1P. second crystal form | x-ray diffraction | A, B, C | — | — |
| 1O6P | Importin Beta bound to a GLFG Nucleoporin peptide | x-ray diffraction | A, B | — | — |
| 1O6P | Importin beta bound to a glfg nucleoporin peptide | x-ray diffraction | A, B | — | — |
| 1QGK | Structure of importin beta bound to the ibb domain of importin alpha | x-ray diffraction | A | — | — |
| 1QGK | Structure of importin beta bound to the ibb domain of importin alpha | x-ray diffraction | A | — | — |
| 1QGR | Structure of importin beta bound to the ibb domain of importin alpha (II crystal form, grown at low… | x-ray diffraction | A | — | — |
| 1QGR | Structure of importin beta bound to the ibb domain of importin alpha (II crystal form, grown at low… | x-ray diffraction | A | — | — |
| 2P8Q | Crystal Structure of human Importin beta bound to the Snurportin1 IBB-domain | x-ray diffraction | A | — | — |
| 2P8Q | Crystal structure of human importin beta bound to the SNURPORTIN1 ibb- domain | x-ray diffraction | A | — | — |
| 2Q5D | Crystal Structure of Human Importin Beta bound to the Snurportin1 IBB-domain second crystal form | x-ray diffraction | A, B | — | — |
| 2Q5D | Crystal structure of human importin beta bound to the SNURPORTIN1 ibb- domain second crystal form | x-ray diffraction | A, B | — | — |
| 2QNA | Crystal structure of human Importin-beta (127-876) in complex with the IBB-domain of Snurportin1… | x-ray diffraction | A | — | — |
| 2QNA | Crystal structure of human importin-beta (127-876) in complex with the ibb-domain of SNURPORTIN1… | x-ray diffraction | A | — | — |
| 3LWW | Structure of an open and closed conformation of Human Importin Beta bound to the Snurportin1… | x-ray diffraction | A, C | — | — |
| 3LWW | Structure of an open and closed conformation of human importin beta bound to the SNURPORTIN1… | x-ray diffraction | A, C | — | — |
| 3W5K | Crystal structure of Snail1 and importin beta complex | x-ray diffraction | A | — | — |
| 3W5K | Crystal structure of SNAIL1 and importin beta complex | x-ray diffraction | A | — | — |
| 6N88 | Cryo-EM structure of the Importin7:Importin beta:Histone H1.0 complex | electron microscopy | B | — | 3 (best 0.57) |
| 6N88 | Cryo-EM structure of the IMPORTIN7:IMPORTIN BETA:HISTONE H1.0 complex | electron microscopy | B | — | — |
| 6N89 | Cryo-EM structure of the importin BETA:HISTONE H1.0 complex | electron microscopy | A | — | — |
| 8GCN | Cryo-EM structure of importin ALPHA1/BETA heterodimer | electron microscopy | A | — | 19 (best 0.80) |
| Q14974 | AlphaFold monomer V2.0 prediction for importin subunit beta-1 (Q14974) | predicted | A | — | — |
Experiment against prediction
- 1QGK chain A against the predicted model Q14974: TM-score 0.99, RMSD 1.12 Å
- 1QGK chain A against the predicted model Q14974: TM-score 0.99, RMSD 1.12 Å
- 2P8Q chain A against the predicted model Q14974: TM-score 0.97, RMSD 1.71 Å
- 2P8Q chain A against the predicted model Q14974: TM-score 0.97, RMSD 1.71 Å
- 3LWW chain A against the predicted model Q14974: TM-score 0.97, RMSD 1.77 Å
- 3LWW chain A against the predicted model Q14974: TM-score 0.97, RMSD 1.77 Å
- 1M5N chain S against the predicted model Q14974: TM-score 0.97, RMSD 1.51 Å
- 1M5N chain S against the predicted model Q14974: TM-score 0.97, RMSD 1.51 Å
- 1F59 chain A against the predicted model Q14974: TM-score 0.96, RMSD 1.55 Å
- 1F59 chain A against the predicted model Q14974: TM-score 0.96, RMSD 1.55 Å
Elsewhere
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