UniProt Q02MM1
CRISPR-associated protein Csy3 (Q02MM1)
CRISPR-associated protein Csy3 (UniProt Q02MM1): 19 experimental structures and 1 predicted model on GenesisL1, 138 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q02MM1
- Protein
- CRISPR-associated protein Csy3
- Experimental structures
- 19
- Predicted models
- 1
- Pockets
- 138 · 8 records with a druggable one
Structures
20 records of Q02MM1 in the MolNFT archive: 19 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5UZ9 | Cryo EM structure of anti-CRISPRs, AcrF1 and AcrF2, bound to type I-F crRNA-guided CRISPR… | electron microscopy | C, D, E, F, G, H | — | 16 (best 0.85) |
| 5UZ9 | Cryo EM structure of anti-crisprs, ACRF1 and ACRF2, bound to type I-F crrna-guided CRISPR… | electron microscopy | C, D, E, F, G, H | — | — |
| 5XLO | Anti-CRISPR proteins AcrF1/2 bound to Csy surveillance complex with a 32nt spacer crRNA backbone… | electron microscopy | A, B, C, D, E, F | — | — |
| 5XLO | Anti-CRISPR proteins ACRF1/2 bound to csy surveillance complex with a 32NT spacer crrna backbone… | electron microscopy | A, B, C, D, E, F | — | — |
| 5XLP | Anti-CRISPR proteins AcrF1/2 bound to Csy surveillance complex with a 20nt spacer crRNA backbone… | electron microscopy | C, D, E, F | — | 20 (best 0.89) |
| 5XLP | Anti-CRISPR proteins ACRF1/2 bound to csy surveillance complex with a 20NT spacer crrna backbone… | electron microscopy | C, D, E, F | — | — |
| 6B44 | Cryo-EM structure of Type I-F CRISPR crRNA-guided Csy surveillance complex with bound target dsDNA | electron microscopy | C, D, E, F, G, H | — | 18 (best 0.86) |
| 6B44 | Cryo-EM structure of type I-F CRISPR crrna-guided csy surveillance complex with bound target dsdna | electron microscopy | C, D, E, F, G, H | — | — |
| 6B45 | Cryo-EM structure of Type I-F CRISPR crRNA-guided Csy surveillance complex | electron microscopy | C, D, E, F, G, H | — | 16 (best 0.83) |
| 6B45 | Cryo-EM structure of type I-F CRISPR crrna-guided csy surveillance complex | electron microscopy | C, D, E, F, G, H | — | — |
| 6B46 | Cryo-EM structure of Type I-F CRISPR crRNA-guided Csy surveillance complex with bound anti-CRISPR… | electron microscopy | C, D, E, F, G, H | — | — |
| 6B46 | Cryo-EM structure of type I-F CRISPR crrna-guided csy surveillance complex with bound anti-CRISPR… | electron microscopy | C, D, E, F, G, H | — | — |
| 6B47 | Cryo-EM structure of Type I-F CRISPR crRNA-guided Csy surveillance complex with bound anti-CRISPR… | electron microscopy | C, D, E, F, G, H | — | 17 (best 0.83) |
| 6B47 | Cryo-EM structure of type I-F CRISPR crrna-guided csy surveillance complex with bound anti-CRISPR… | electron microscopy | C, D, E, F, G, H | — | — |
| 6B48 | Cryo-EM structure of Type I-F CRISPR crRNA-guided Csy surveillance complex with bound anti-CRISPR… | electron microscopy | C, D, E, F, G, H | — | 18 (best 0.88) |
| 6B48 | Cryo-EM structure of type I-F CRISPR crrna-guided csy surveillance complex with bound anti-CRISPR… | electron microscopy | C, D, E, F, G, H | — | — |
| 6NE0 | Structure of double-stranded target DNA engaged Csy complex from Pseudomonas aeruginosa (PA-14) | electron microscopy | C, D, E, F, G, H | — | 17 (best 0.85) |
| 6NE0 | Structure of double-stranded target DNA engaged csy complex from pseudomonas aeruginosa (pa-14) | electron microscopy | C, D, E, F, G, H | — | — |
| 8JDI | Crystal structure of Cas7-AcrIF25 complex | x-ray diffraction | A, C, B, D | — | 16 (best 0.78) |
| Q02MM1 | AlphaFold monomer V2.0 prediction for CRISPR-associated protein CSY3 (Q02MM1) | predicted | A | — | — |
Experiment against prediction
- 6B47 chain C against the predicted model Q02MM1: TM-score 0.98, RMSD 0.89 Å
- 6B47 chain C against the predicted model Q02MM1: TM-score 0.98, RMSD 0.89 Å
- 6B47 chain H against the predicted model Q02MM1: TM-score 0.98, RMSD 0.97 Å
- 6B47 chain H against the predicted model Q02MM1: TM-score 0.98, RMSD 0.97 Å
- 6NE0 chain C against the predicted model Q02MM1: TM-score 0.98, RMSD 0.89 Å
- 6NE0 chain C against the predicted model Q02MM1: TM-score 0.98, RMSD 0.89 Å
- 6B46 chain C against the predicted model Q02MM1: TM-score 0.98, RMSD 0.90 Å
- 6B46 chain C against the predicted model Q02MM1: TM-score 0.98, RMSD 0.90 Å
- 5UZ9 chain C against the predicted model Q02MM1: TM-score 0.98, RMSD 0.92 Å
- 5UZ9 chain C against the predicted model Q02MM1: TM-score 0.98, RMSD 0.92 Å
Elsewhere
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