UniProt P68363
Tubulin alpha-1B chain (P68363)
Tubulin alpha-1B chain (UniProt P68363), EC 3.6.5.-: 39 experimental structures on GenesisL1, 6 ligands bound, 131 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- P68363
- Protein
- Tubulin alpha-1B chain
- EC
- 3.6.5.-
- Experimental structures
- 39
- Predicted models
- 0
- Ligands
- 6
- Pockets
- 131 · 11 records with a druggable one
Structures
39 records of P68363 in the MolNFT archive: 39 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2E4H | Solution structure of cytoskeletal protein in complex with tubulin tail | solution nmr | B | — | — |
| 2E4H | Solution structure of cytoskeletal protein in complex with tubulin tail | solution nmr | B | — | — |
| 5IJ0 | Cryo EM density of microtubule assembled from human TUBB3 | electron microscopy | A | GTP, MG | — |
| 5IJ0 | Cryo EM density of microtubule assembled from human TUBB3 | electron microscopy | A | — | — |
| 5IJ9 | Cryo EM density of microtubule assembled from human TUBB3-D417H mutant | electron microscopy | A | GTP, MG | — |
| 5IJ9 | Cryo EM density of microtubule assembled from human TUBB3-D417H mutant | electron microscopy | A | — | — |
| 5N5N | Cryo-EM structure of tsA201 cell alpha1B and betaI and betaIVb microtubules | electron microscopy | K, G, H, I, J, L | G2P, GTP, MG | 16 (best 0.85) |
| 5N5N | Cryo-EM structure of TSA201 cell ALPHA1B and betai and betaivb microtubules | electron microscopy | K, G, H, I, J, L | G2P, GTP, MG | — |
| 6E7B | 13-pf 3-start GMPCPP-human alpha1B/beta3 microtubules | electron microscopy | A | MG, GTP | 6 (best 0.83) |
| 6E7B | 13-pf 3-start gmpcpp-human ALPHA1B/BETA3 microtubules | electron microscopy | A | MG, GTP | — |
| 6E7C | 14-pf 3-start GMPCPP-human alpha1B/beta2B microtubules | electron microscopy | A | MG, GTP | 4 (best 0.83) |
| 6E7C | 14-pf 3-start gmpcpp-human ALPHA1B/BETA2B microtubules | electron microscopy | A | MG, GTP | — |
| 6I2I | Refined 13pf Hela Cell Tubulin microtubule (EML4-NTD decorated) | electron microscopy | A | GTP, MG, G2P | — |
| 6I2I | Refined 13PF hela cell tubulin microtubule (EML4-ntd decorated) | electron microscopy | A | GTP, MG, G2P | — |
| 6J4V | Structural basis of tubulin detyrosination by vasohibins-svbp enzyme complex and functional… | x-ray diffraction | C | — | — |
| 6QUS | Hsckk (human CAMSAP1) decorated 13PF taxol-GDP microtubule | electron microscopy | X, O | GTP, MG | — |
| 6QUY | NgCKK (N.Gruberi CKK) decorated 13pf taxol-GDP microtubule | electron microscopy | A, C | GTP, MG | 13 (best 0.84) |
| 6QUY | Ngckk (N.GRUBERI ckk) decorated 13PF taxol-GDP microtubule | electron microscopy | A, C | GTP, MG | — |
| 6QVE | Ngckk (naegleria gruberi ckk) decorated 14PF taxol-GDP microtubule | electron microscopy | C, A | GTP, MG | — |
| 6QVJ | HsCKK (human CAMSAP1) decorated 14pf taxol-GDP microtubule | electron microscopy | O, X | GTP, MG | — |
| 6QVJ | Hsckk (human CAMSAP1) decorated 14PF taxol-GDP microtubule | electron microscopy | O, X | GTP, MG | — |
| 6S8L | Structure, Thermodynamics, and Kinetics of Plinabulin Binding to two Tubulin Isotypes | x-ray diffraction | A | GTP, MG | 7 (best 0.81) |
| 6S8L | Structure, thermodynamics, and kinetics of plinabulin binding to two tubulin isotypes | x-ray diffraction | A | GTP | — |
| 7LXB | Hela-tubulin in complex with cryptophycin 52 | electron microscopy | A, C, E, G, I, K, M, O | GTP, YGY | — |
| 7M18 | Hela-tubulin in complex with cryptophycin 1 | electron microscopy | A, C, E, G, I, K, M, O | YNP, GTP | — |
| 7M20 | 18-mer hela-tubulin rings in complex with cryptophycin 1 | electron microscopy | A, C, E, G, I, K, M, O, Q | YNP, GTP | — |
| 7PJF | Inhibiting parasite proliferation using a rationally designed anti- tubulin agent | x-ray diffraction | A | GTP, MG | — |
| 7SJ7 | Undecorated 13PF wildtype microtubule from recombinant human tubulin | electron microscopy | A, C, E, J, K, L | GTP, MG | — |
| 7SJ8 | 13pf wildtype microtubule from recombinant human tubulin decorated with kinesin | electron microscopy | A, C, E, J, K, L | GTP, MG, GDP | 15 (best 0.86) |
| 7SJ8 | 13PF wildtype microtubule from recombinant human tubulin decorated with kinesin | electron microscopy | A, C, E, J, K, L | GTP, MG | — |
| 7SJ9 | 13PF E254A microtubule from recombinant human tubulin decorated with EB3 | electron microscopy | A, C, E, J, K, L | GTP, MG | — |
| 7SJA | Undecorated 13PF E254N microtubule from recombinant human tubulin | electron microscopy | A, C, E, J, K, L | GTP, MG | — |
| 7Z6S | MATCAP bound to a human 14 protofilament microtubule | electron microscopy | A, K | GTP, MG, GDP | 17 (best 0.84) |
| 7Z6S | Matcap bound to a human 14 protofilament microtubule | electron microscopy | A, K | GTP, MG | — |
| 8U3Z | Model of TTLL6 bound to microtubule from composite map | electron microscopy | A, F | GTP, MG, G2P | 8 (best 0.86) |
| 8VRJ | Rigid body fitted model for gamma tubulin ring complex capped microtubule | electron microscopy | 1, O, P, Q, R, S, T, U, V, W, X, Y, Z | — | 15 (best 0.87) |
| 8VT7 | Structure of the gamma tubulin ring complex nucleated microtubule protofilament. | electron microscopy | J, B | GTP, MG, GDP | 16 (best 0.83) |
| 9BP6 | Structure of alpha1B and betaI/IVb microtubule bound to GMPCPP | electron microscopy | A, I | GTP, MG, G2P | 14 (best 0.83) |
| P68363 | AlphaFold monomer V2.0 prediction for tubulin alpha-1B chain (P68363) | — | — | — |
Ligands
Elsewhere
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