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UniProt P58743

Prestin (P58743)

Prestin (UniProt P58743): 4 experimental structures and 1 predicted model on GenesisL1, 7 ligands bound, 8 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.

UniProt
P58743
Protein
Prestin
Experimental structures
4
Predicted models
1
Ligands
7
Pockets
8 · 1 record with a druggable one

Structures

5 records of P58743 in the MolNFT archive: 4 experimental, 1 predicted.

EntryTitleMethodChainsLigandsPockets
7LGUStructure of human prestin in the presence of naclelectron microscopyA, BCL, CLR, D12, D10, HP6, C14—
7LGWStructure of human prestin in nanodisc in the presence of naclelectron microscopyA, BCL, CLR, D12, D10, HP6, C14—
7LH2Structure of human prestin in the presence of sodium salicylate and sodium sulfateelectron microscopyA, BSAL, CLR—
7LH3Structure of human prestin in the presence of sodium sulfateelectron microscopyA, B——
P58743AlphaFold monomer V2.0 prediction for prestin (P58743)predictedA—8 (best 0.76)

Ligands

  • CLR · Cholesterol · in 3 records
  • C14 · Tetradecane · in 2 records
  • CL · Chloride ion · in 2 records
  • D10 · Decane · in 2 records
  • D12 · Dodecane · in 2 records
  • HP6 · Heptane · in 2 records
  • SAL · 2-hydroxybenzoic acid · in 1 record

Experiment against prediction

Elsewhere

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