MolNFT v1 · #418827 · protein
AlphaFold monomer V2.0 prediction for prestin (P58743)
P58743: “AlphaFold monomer V2.0 prediction for prestin (P58743)”. 8 pockets (best druggability 0.76). MolNFT v1 #418827 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P58743
- Type
- protein
- Length
- 744 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xF25799609c3112487CBaCFd8059A5b2D59a35379
- Molecule
- Prestin
- UniProt
- P58743
- Pockets
- 8 · best druggability 0.76
Structure
1 distinct chain · 62% helix, 5% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Prestin | protein | 744 | 62% helix, 5% strand | P58743 |
Pockets
8 pockets found on a 1 Å grid, 5 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 157 | 0.76 | 0.93 | 31 | empty |
| 2 | 343 | 0.69 | 0.82 | 39 | empty |
| 3 | 331 | 0.60 | 0.78 | 32 | empty |
| 4 | 298 | 0.57 | 0.77 | 34 | empty |
| 5 | 178 | 0.56 | 0.80 | 26 | empty |
Compared structures
- 7LH3 · Structure of human prestin in the presence of sodium sulfate · an experimental structure of the same protein · chain A against B, TM-score 0.85
- 7LH3 · Structure of human prestin in the presence of sodium sulfate · an experimental structure of the same protein · chain A against A, TM-score 0.85
- 7LH2 · Structure of human prestin in the presence of sodium salicylate and sodium sulfate · an experimental structure of the same protein · chain A against A, TM-score 0.85
- 7LH2 · Structure of human prestin in the presence of sodium salicylate and sodium sulfate · an experimental structure of the same protein · chain A against A, TM-score 0.85
- 7LGU · Structure of human prestin in the presence of nacl · an experimental structure of the same protein · chain A against A, TM-score 0.83
- 7LGU · Structure of human prestin in the presence of NaCl · an experimental structure of the same protein · chain A against A, TM-score 0.83
- 7LGW · Structure of human Prestin in nanodisc in the presence of NaCl · an experimental structure of the same protein · chain A against A, TM-score 0.83
- 7LGW · Structure of human prestin in nanodisc in the presence of nacl · an experimental structure of the same protein · chain A against A, TM-score 0.83
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P58743
- Elsewhere: UniProt P58743 · AlphaFold DB P58743
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