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AlphaFold monomer V2.0 prediction for prestin (P58743)

Analyse AlphaFold monomer V2.0 prediction for prestin (P58743) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

Accession
P58743
Type
protein
Length
744 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0xF25799609c3112487CBaCFd8059A5b2D59a35379
Molecule
Prestin
UniProt
P58743
Pockets
8 · best druggability 0.76

Structure

1 distinct chain · 62% helix, 5% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
APrestinprotein74462% helix, 5% strandP58743

Pockets

8 pockets found on a 1 Å grid, 5 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
11570.760.9331empty
23430.690.8239empty
33310.600.7832empty
42980.570.7734empty
51780.560.8026empty

Compared structures

  • 7LH3 · Structure of human prestin in the presence of sodium sulfate · an experimental structure of the same protein · chain A against B, TM-score 0.85
  • 7LH3 · Structure of human prestin in the presence of sodium sulfate · an experimental structure of the same protein · chain A against A, TM-score 0.85
  • 7LH2 · Structure of human prestin in the presence of sodium salicylate and sodium sulfate · an experimental structure of the same protein · chain A against A, TM-score 0.85
  • 7LH2 · Structure of human prestin in the presence of sodium salicylate and sodium sulfate · an experimental structure of the same protein · chain A against A, TM-score 0.85
  • 7LGU · Structure of human prestin in the presence of nacl · an experimental structure of the same protein · chain A against A, TM-score 0.83
  • 7LGU · Structure of human prestin in the presence of NaCl · an experimental structure of the same protein · chain A against A, TM-score 0.83
  • 7LGW · Structure of human Prestin in nanodisc in the presence of NaCl · an experimental structure of the same protein · chain A against A, TM-score 0.83
  • 7LGW · Structure of human prestin in nanodisc in the presence of nacl · an experimental structure of the same protein · chain A against A, TM-score 0.83

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