UniProt P56109
Fructose-bisphosphate aldolase (P56109)
Fructose-bisphosphate aldolase (UniProt P56109), EC 4.1.2.13: 26 experimental structures and 1 predicted model on GenesisL1, 7 ligands bound, 18 pockets. Binding sites, druggability and experiment against prediction (TM-score) in…
- UniProt
- P56109
- Protein
- Fructose-bisphosphate aldolase
- EC
- 4.1.2.13
- Experimental structures
- 26
- Predicted models
- 1
- Ligands
- 7
- Pockets
- 18 · 1 record with a druggable one
Structures
27 records of P56109 in the MolNFT archive: 26 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3C4U | Structure of class II fructose-biphosphate aldolase from helicobacter pylori | x-ray diffraction | A, B | — | — |
| 3C4U | Structure of class II fructose-biphosphate aldolase from helicobacter pylori | x-ray diffraction | A, B | — | — |
| 3C52 | Class II fructose-1,6-bisphosphate aldolase from helicobacter pylori in complex with… | x-ray diffraction | A, B | — | — |
| 3C52 | Class II fructose-1,6-bisphosphate aldolase from helicobacter pylori in complex with… | x-ray diffraction | A, B | — | — |
| 3C56 | Class II fructose-1,6-bisphosphate aldolase from helicobacter pylori in complex with… | x-ray diffraction | A, B | — | — |
| 3C56 | Class II fructose-1,6-bisphosphate aldolase from helicobacter pylori in complex with… | x-ray diffraction | A, B | — | — |
| 5UCK | Class II fructose-1,6-bisphosphate aldolase of Helicobacter pylori with cleavage products | x-ray diffraction | A, B | NA, ZN, 13P, G3H | 4 (best 0.47) |
| 5UCK | Class II fructose-1,6-bisphosphate aldolase of helicobacter pylori with cleavage products | x-ray diffraction | A, B | NA, ZN, 13P, G3H | — |
| 5UCN | Class II fructose-1,6-bisphosphate aldolase E142A variant of Helicobacter pylori with DHAP | x-ray diffraction | A, B | NA, ZN, 13P | — |
| 5UCN | Class II fructose-1,6-bisphosphate aldolase E142A variant of helicobacter pylori with dhap | x-ray diffraction | A, B | NA, ZN, 13P | — |
| 5UCP | Class II fructose-1,6-bisphosphate aldolase E142A variant of Helicobacter pylori with FBP and… | x-ray diffraction | A, B | NA, ZN, P6F, 13P, G3H | 3 (best 0.45) |
| 5UCP | Class II fructose-1,6-bisphosphate aldolase E142A variant of helicobacter pylori with fbp and… | x-ray diffraction | A, B | NA, ZN, P6F, 13P, G3H | — |
| 5UCS | Class II fructose-1,6-bisphosphate aldolase E149A variant of Helicobacter pylori | x-ray diffraction | A, B | NA, ZN | — |
| 5UCS | Class II fructose-1,6-bisphosphate aldolase E149A variant of helicobacter pylori | x-ray diffraction | A, B | NA, ZN | — |
| 5UCZ | Class II fructose-1,6-bisphosphate aldolase E149A variant of Helicobacter pylori with DHAP | x-ray diffraction | A, B | NA, ZN, 13P | 4 (best 0.54) |
| 5UCZ | Class II fructose-1,6-bisphosphate aldolase E149A variant of helicobacter pylori with dhap | x-ray diffraction | A, B | NA, ZN, 13P | — |
| 5UD0 | Class II fructose-1,6-bisphosphate aldolase E149A variant of Helicobacter pylori with cleavage… | x-ray diffraction | A, B | NA, ZN, CA, 13P, G3H | 3 (best 0.45) |
| 5UD0 | Class II fructose-1,6-bisphosphate aldolase E149A variant of helicobacter pylori with cleavage… | x-ray diffraction | A, B | NA, ZN, CA, 13P, G3H | — |
| 5UD1 | Class II fructose-1,6-bisphosphate aldolase H180Q variant of Helicobacter pylori | x-ray diffraction | A, B | NA, ZN | — |
| 5UD1 | Class II fructose-1,6-bisphosphate aldolase H180Q variant of helicobacter pylori | x-ray diffraction | A, B | NA, ZN | — |
| 5UD2 | Class II fructose-1,6-bisphosphate aldolase H180Q variant of helicobacter pylori with dhap | x-ray diffraction | A, B | NA, ZN, 13P | — |
| 5UD3 | Class II fructose-1,6-bisphosphate aldolase H180Q variant of Helicobacter pylori with FBP | x-ray diffraction | A, B | NA, ZN, P6F | 4 (best 0.46) |
| 5UD3 | Class II fructose-1,6-bisphosphate aldolase H180Q variant of helicobacter pylori with fbp | x-ray diffraction | A, B | NA, ZN, P6F | — |
| 5UD4 | Class II fructose-1,6-bisphosphate aldolase H180Q variant of helicobacter pylori with tbp | x-ray diffraction | A, B | NA, ZN, P6T | — |
| 5VJF | Class II fructose-1,6-bisphosphate aldolase of Helicobacter pylori with DHAP | x-ray diffraction | A, B | ZN, NA, CA, 13P | — |
| 5VJF | Class II fructose-1,6-bisphosphate aldolase of helicobacter pylori with dhap | x-ray diffraction | A, B | ZN, NA, CA, 13P | — |
| P56109 | AlphaFold monomer V2.0 prediction for fructose-bisphosphate aldolase (P56109) | predicted | A | — | — |
Ligands
Experiment against prediction
- 5UD1 chain A against the predicted model P56109: TM-score 1.00, RMSD 0.41 Å
- 5UD1 chain A against the predicted model P56109: TM-score 1.00, RMSD 0.41 Å
- 5UD2 chain B against the predicted model P56109: TM-score 1.00, RMSD 0.44 Å
- 5UD1 chain B against the predicted model P56109: TM-score 1.00, RMSD 0.43 Å
- 5UD1 chain B against the predicted model P56109: TM-score 1.00, RMSD 0.43 Å
- 5UCN chain A against the predicted model P56109: TM-score 1.00, RMSD 0.45 Å
- 5UCN chain A against the predicted model P56109: TM-score 1.00, RMSD 0.45 Å
- 5UCN chain B against the predicted model P56109: TM-score 0.99, RMSD 0.45 Å
- 5UCN chain B against the predicted model P56109: TM-score 0.99, RMSD 0.45 Å
- 5UCZ chain A against the predicted model P56109: TM-score 0.99, RMSD 0.45 Å
Elsewhere
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