MolNFT v1 · #135907 · protein
Class II fructose-1,6-bisphosphate aldolase H180Q variant of helicobacter pylori
5UD1 · Fructose-bisphosphate aldolase: “Class II fructose-1,6-bisphosphate aldolase H180Q variant of helicobacter pylori”. X-ray diffraction, 2 ligands (ZN, NA), 2 pockets (best druggability 0.44). MolNFT v1 #135907 on GenesisL1: 3D…
- PDB
- 5UD1
- Type
- protein
- Length
- 556 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Fructose-bisphosphate aldolase
- EC
- 4.1.2.13
- UniProt
- P56109
- Ligands
- ZN, NA
- Pockets
- 2 · best druggability 0.44
Structure
x-ray diffraction · 1 distinct chain · 55% helix, 15% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Fructose-bisphosphate aldolase (EC 4.1.2.13) | protein | 278 | 55% helix, 15% strand | P56109 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 97 | 0.44 | 0.79 | 22 | ZN |
| 2 | 60 | 0.27 | 0.73 | 17 | empty |
Interfaces
1 interface between chains.
- A–B · 1934 Ų buried · 32 hydrogen bonds · protein-protein
Compared structures
- 5UD1 · Class II fructose-1,6-bisphosphate aldolase H180Q variant of Helicobacter pylori · the same entry in another collection · chain A against A, TM-score 1.00
- P56109 · AlphaFold monomer V2.0 prediction for fructose-bisphosphate aldolase (P56109) · a predicted model of the same protein · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P56109
- Elsewhere: RCSB PDB 5UD1 · PDBe 5UD1 · UniProt P56109
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.